Introduction: The Challenge of Early Amyotrophic Lateral Sclerosis (ALS) Detection
ALS, also known as Lou Gehrig’s disease, is a devastating neurodegenerative disorder characterized by progressive loss of motor neurons, leading to muscle weakness, paralysis, and eventually death. Traditionally, ALS diagnosis has relied upon the emergence of clinical symptoms such as muscle twitching, weakness, and difficulty speaking or swallowing. However, by this stage, irreversible neurological damage has often occurred, limiting therapeutic intervention. Understanding and identifying ALS at its earliest stages remain a vital unmet need in neurology and patient care.
