E-cigarettes versus Combination Nicotine Replacement Therapy for Smoking Cessation in Substance Use Disorder Patients: Integrative Analysis of Recent Trials and Longitudinal Patterns
Posted inClinical Updates news Psychiatry Specialties

E-cigarettes versus Combination Nicotine Replacement Therapy for Smoking Cessation in Substance Use Disorder Patients: Integrative Analysis of Recent Trials and Longitudinal Patterns

Recent trials show no significant difference in smoking cessation rates between e-cigarettes and combination nicotine replacement therapy among patients discharged from inpatient substance use withdrawal services. Longitudinal analyses reveal variable abstinence trajectories in e-cigarette trials, underscoring the need for further relapse-focused research.
Distinct Genomic Mutation Patterns in Early-Onset Colorectal Cancer: Implications for Clinical Stratification and Precision Medicine
Posted inClinical Updates Gastroenterology news Oncology Pathology & Lab Medicine Specialties

Distinct Genomic Mutation Patterns in Early-Onset Colorectal Cancer: Implications for Clinical Stratification and Precision Medicine

A large international study reveals unique somatic mutation profiles and higher mutational burden in hypermutated early-onset colorectal cancer, highlighting the need for age-specific molecular diagnostics and management strategies.