SURE-02 Trial: Neoadjuvant Sacituzumab Govitecan and Pembrolizumab Enable Bladder Preservation in Muscle-Invasive Disease

Highlights

The study reported a clinical complete response (cCR) rate of 39% (95% CI 25-54) in patients with muscle-invasive bladder cancer (MIBC) who were ineligible for or declined cisplatin-based chemotherapy.

No grade 4 or higher treatment-related adverse events occurred, with grade 3 events limited to 16% of the cohort, primarily diarrhea.

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