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  • Page 57
Refining Prostate Cancer Risk Prediction in Men of African Ancestry: Integrating Pathogenic Variants, Polygenic Scores, and Family History
Posted innews Oncology Urology

Refining Prostate Cancer Risk Prediction in Men of African Ancestry: Integrating Pathogenic Variants, Polygenic Scores, and Family History

Posted by MedXY By MedXY 12/17/2025
This study identifies key germline variants and demonstrates how combining genetic data with family history improves personalized prostate cancer risk assessment in men of African ancestry, guiding future screening strategies.
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Personalizing Breast Cancer Screening: Insights from the WISDOM Trial on Risk-Based vs Annual Mammography
Posted innews Oncology

Personalizing Breast Cancer Screening: Insights from the WISDOM Trial on Risk-Based vs Annual Mammography

Posted by MedXY By MedXY 12/17/2025
The WISDOM trial shows risk-based breast cancer screening using genetic and clinical data as a safe alternative to annual mammography, tailoring screening frequency by individual risk without increasing advanced cancer rates.
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Prophylactic Strategies to Prevent Infection in Lower Limb Peripheral Arterial Reconstruction: Evidence and Clinical Implications
Posted inCardiology Infectious Diseases news

Prophylactic Strategies to Prevent Infection in Lower Limb Peripheral Arterial Reconstruction: Evidence and Clinical Implications

Posted by MedXY By MedXY 12/17/2025
Cochrane review shows prophylactic antibiotics may reduce SSI risk in peripheral arterial reconstruction; closed incision negative pressure therapy offers possible benefit but evidence is low.
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Chemoendocrine Therapy Linked to Greater Cognitive Decline in Breast Cancer Patients, Regardless of Menopausal Status
Posted inNeurology news Oncology

Chemoendocrine Therapy Linked to Greater Cognitive Decline in Breast Cancer Patients, Regardless of Menopausal Status

Posted by MedXY By MedXY 12/17/2025
A secondary analysis of the RxPONDER trial finds chemoendocrine therapy causes more lasting cognitive impairment than endocrine therapy alone in both pre- and postmenopausal women.
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Biofeedback vs Respiratory Retraining: No Significant Difference in Inducible Laryngeal Obstruction Relief
Posted innews Otorhinolaryngology Respiratory

Biofeedback vs Respiratory Retraining: No Significant Difference in Inducible Laryngeal Obstruction Relief

Posted by MedXY By MedXY 12/17/2025
A pilot trial finds biofeedback and respiratory retraining equally effective for inducible laryngeal obstruction, offering clinicians flexible, patient-tailored options.
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Elevated Serotonin Release in Schizophrenia: New Insights Into Negative Symptom Pathophysiology
Posted inNeurology news Psychiatry

Elevated Serotonin Release in Schizophrenia: New Insights Into Negative Symptom Pathophysiology

Posted by MedXY By MedXY 12/17/2025
A PET imaging study reveals increased frontal serotonin release in schizophrenia, particularly in deficit type, tied to worse negative symptoms.
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Combined Cardiorespiratory and Resistance Training After Stroke: Small Gains, Big Questions
Posted inCardiology Neurology news

Combined Cardiorespiratory and Resistance Training After Stroke: Small Gains, Big Questions

Posted by MedXY By MedXY 12/17/2025
Evidence suggests combined aerobic and strength training post-stroke yields modest improvements in fitness and function but uncertain long-term benefits.
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Do Behavioural, Self-Management, and Service Delivery Models Improve Outcomes in Adults with Epilepsy?
Posted inNeurology news

Do Behavioural, Self-Management, and Service Delivery Models Improve Outcomes in Adults with Epilepsy?

Posted by MedXY By MedXY 12/17/2025
A Cochrane review finds limited and low- to moderate-certainty evidence that behavioural, self-management, or service delivery interventions improve seizure control or quality of life in adults with epilepsy.
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Omega-3 Fatty Acids Show Limited Benefits for Diabetic Peripheral Neuropathy
Posted inDiabetes & Endocrinology Neurology news

Omega-3 Fatty Acids Show Limited Benefits for Diabetic Peripheral Neuropathy

Posted by MedXY By MedXY 12/17/2025
Current evidence suggests minimal impact of omega-3 supplementation on neuropathy symptoms or quality of life in adults with diabetes.
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Progestagens Show Promise for Pain Relief in Endometriosis, With Nuanced Efficacy Across Comparators
Posted innews

Progestagens Show Promise for Pain Relief in Endometriosis, With Nuanced Efficacy Across Comparators

Posted by MedXY By MedXY 12/17/2025
Oral progestagens likely reduce overall pain and dysmenorrhoea in endometriosis, but comparative benefits over other hormonal treatments remain uncertain.
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Rare but High-Risk: New-Onset RBBB After TAVR Strongly Linked to Pacemaker Need
Posted inCardiology news

Rare but High-Risk: New-Onset RBBB After TAVR Strongly Linked to Pacemaker Need

Posted by MedXY By MedXY 12/17/2025
New-onset right bundle branch block after TAVR is rare but carries a high risk of requiring permanent pacing within one week.
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Prophylactic Pacemakers After TAVR: Low Pacing Burden Raises Questions on Routine Use
Posted inCardiology news

Prophylactic Pacemakers After TAVR: Low Pacing Burden Raises Questions on Routine Use

Posted by MedXY By MedXY 12/17/2025
One-fourth of TAVR patients receive prophylactic pacemakers, but most have minimal pacing needs at 30 days.
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PROMOTE Study Validates Algorithm for Conduction Disturbance Management After TAVR
Posted inCardiology news

PROMOTE Study Validates Algorithm for Conduction Disturbance Management After TAVR

Posted by MedXY By MedXY 12/17/2025
A prospective multicenter study confirms that a prespecified algorithm for conduction disturbance management after TAVR is safe, with low sudden cardiac death risk but persistent high pacemaker rates.
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Distinct Mechanisms Drive Early and Delayed Heart Block After TAVR: Insights from Boston Cohort Study
Posted inCardiology news

Distinct Mechanisms Drive Early and Delayed Heart Block After TAVR: Insights from Boston Cohort Study

Posted by MedXY By MedXY 12/17/2025
Prospective cohort study reveals AV nodal versus infranodal conduction patterns underpinning timing of heart block after TAVR.
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Cryotherapy After Total Knee Replacement: Limited Evidence for Modest Benefits
Posted innews Orthopedics

Cryotherapy After Total Knee Replacement: Limited Evidence for Modest Benefits

Posted by MedXY By MedXY 12/16/2025
Low-certainty evidence suggests cryotherapy may slightly reduce blood loss, pain, and swelling after total knee replacement, but clinical relevance remains uncertain.
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Rethinking Oxygen Strategies for Preterm Infant Resuscitation: Evidence from TORPIDO, IPD-MA, and DCC Trials
Posted inCritical Care news Pediatrics

Rethinking Oxygen Strategies for Preterm Infant Resuscitation: Evidence from TORPIDO, IPD-MA, and DCC Trials

Posted by MedXY By MedXY 12/16/2025
Recent trials and meta-analyses challenge assumptions about optimal initial oxygen levels for preterm resuscitation.
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Broad Genetic Testing Reveals Hidden Breast Cancer Risk in Women Without Family History
Posted innews Oncology

Broad Genetic Testing Reveals Hidden Breast Cancer Risk in Women Without Family History

Posted by MedXY By MedXY 12/16/2025
The WISDOM trial found that 3.1% of women without breast cancer carried pathogenic variants in key susceptibility genes, many outside existing testing guidelines.
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Progestagens Show Moderate Efficacy for Endometriosis Pain, But Evidence Variability Limits Clinical Certainty
Posted innews OB/GYN & Women's Health

Progestagens Show Moderate Efficacy for Endometriosis Pain, But Evidence Variability Limits Clinical Certainty

Posted by MedXY By MedXY 12/16/2025
Oral progestagens reduce overall pain and dysmenorrhoea in endometriosis, but comparative benefits over other hormonal therapies remain uncertain.
Read More
Simple vs Radical Hysterectomy: Balancing Survival Outcomes and Quality of Life in Early Cervical Cancer
Posted innews OB/GYN & Women's Health Oncology

Simple vs Radical Hysterectomy: Balancing Survival Outcomes and Quality of Life in Early Cervical Cancer

Posted by MedXY By MedXY 12/16/2025
Evidence suggests simple hysterectomy with pelvic lymphadenectomy may offer similar survival outcomes to radical hysterectomy in early-stage cervical cancer, with fewer adverse events and better short-term quality of life.
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Immediate and Early Skin-to-Skin Contact After Birth: What the 2025 Cochrane Update Means for Practice
Posted innews OB/GYN & Women's Health Pediatrics

Immediate and Early Skin-to-Skin Contact After Birth: What the 2025 Cochrane Update Means for Practice

Posted by MedXY By MedXY 12/16/2025
A clear, evidence-based summary of the 2025 Cochrane review on immediate/early skin-to-skin contact (SSC), its impact on breastfeeding and newborn physiology, gaps in maternal outcomes, and practical recommendations for clinical implementation.
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  • Lupuslike Manifestations in Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: A Case-Cohort Analysis of Clonal Inflammation
  • Validating the Patient’s Voice in Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis of Patient-Reported Outcome Measures
  • The Era of the ‘Virtual Biopsy’: Cross-Modal Imaging and the Noninvasive Identification of Skin Histology
  • The TIP-CA Model: A Validated Tool to Stratify Cancer Risk in Adult Dermatomyositis Patients
  • SURE-02 Trial: Neoadjuvant Sacituzumab Govitecan and Pembrolizumab Enable Bladder Preservation in Muscle-Invasive Disease
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