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Age, Tumor Size, and Weight in Early-Stage Favorable Histology Wilms Tumor: Reevaluating Prognostic Indicators with COG Data

By MedXY 10/09/2026

This pooled analysis from COG studies reveals that after accounting for tumor biology, age, tumor nephrectomy weight, and diameter are not independently predictive of outcomes in stage I/II favorable histology Wilms tumor, refining risk stratification strategies.

Hematology-Oncology news

Lymph Node Assessment and Survival Outcomes in Favorable Histology Wilms Tumor: Insights from a Large COG Renal Tumor Study

By MedXY 09/13/2026

This study evaluates how the number and positivity of lymph nodes affect survival outcomes in over 2,000 patients with stage I–III favorable histology Wilms tumor, underscoring the need for standardized lymph node sampling in surgical staging.

news Oncology Pediatrics

Chromosome 1q Gain, Not Lung Nodule Burden, Best Predicts Outcomes in Stage IV Favorable‑Histology Wilms Tumor

By MedXY 12/08/2025

In AREN0533, number and size of pulmonary metastases had limited prognostic value after standardized therapy; gain of chromosome 1q emerged as a stronger, independent predictor of event‑free and overall survival in children with favorable‑histology Wilms tumor and lung‑only metastases.