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TRPV4

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Targeting the TRPV4-RhoA-RhoGDI1 Axis: A Novel Approach for Hypertension Therapy
Posted inCardiology Specialties

Targeting the TRPV4-RhoA-RhoGDI1 Axis: A Novel Approach for Hypertension Therapy

Posted by By MedXY 09/07/2025
A novel inhibitor AH001 targets the TRPV4-RhoA-RhoGDI1 axis to inactivate RhoA signaling, effectively reducing blood pressure and preventing vascular remodeling in hypertensive models, opening new avenues for antihypertensive drug development.
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