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SMAD Signaling

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Hypoxia-Induced BACH1 Elevation Drives Pulmonary Hypertension via Activation of TGFBR2/SMAD Signaling
Posted inCardiology news Respiratory

Hypoxia-Induced BACH1 Elevation Drives Pulmonary Hypertension via Activation of TGFBR2/SMAD Signaling

Posted by By MedXY 07/15/2026
BACH1 stabilization under hypoxia promotes pulmonary hypertension by enhancing TGFBR2/SMAD pathway activity in pulmonary artery smooth muscle cells, suggesting BACH1 as a promising therapeutic target for PH.
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