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PRMT9

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Epigenetic Regulation of Myocardial Inflammation: The Role of Macrophage PRMT9 and STAT1 Degradation in Acute Myocardial Infarction
Posted inCardiology Clinical Updates news

Epigenetic Regulation of Myocardial Inflammation: The Role of Macrophage PRMT9 and STAT1 Degradation in Acute Myocardial Infarction

Posted by MedXY By MedXY 05/05/2026
This review explores how PRMT9-mediated symmetric dimethylation of STAT1 serves as a critical check on proinflammatory macrophage activation, offering a novel therapeutic target for mitigating cardiac injury following myocardial infarction.
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PRMT9 and Heart Recovery: A New Frontier in Macrophage Modulation and STAT1 Degradation
Posted inCardiology news

PRMT9 and Heart Recovery: A New Frontier in Macrophage Modulation and STAT1 Degradation

Posted by MedXY By MedXY 03/02/2026
Researchers have discovered that the protein PRMT9 plays a vital role in healing the heart after a myocardial infarction by controlling inflammatory macrophages. By promoting the degradation of the STAT1 protein, PRMT9 reduces tissue damage and improves cardiac function.
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