Navigating Prolactinomas in Pregnancy: An Evidence-Based Approach for Optimal Maternal and Fetal Outcomes

Navigating Prolactinomas in Pregnancy: An Evidence-Based Approach for Optimal Maternal and Fetal Outcomes

Prolactinomas, common pituitary adenomas in reproductive-age women, challenge pregnancy management due to risks of tumor growth and hormonal shifts. This article reviews current strategies for diagnosis, treatment, and monitoring before, during, and after pregnancy to ensure safety and fertility restoration.
Precision Risk Stratification in Cushing’s Disease: Integrating USP8 Genotype and Tumor Size to Predict Long-Term Recurrence

Precision Risk Stratification in Cushing’s Disease: Integrating USP8 Genotype and Tumor Size to Predict Long-Term Recurrence

An international cohort study demonstrates that combining USP8 genotype with tumor size significantly improves the prediction of recurrence in Cushing's disease, identifying high-risk patients even among those with low postoperative cortisol levels, paving the way for personalized long-term follow-up.