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patent ductus arteriosus

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Prophylactic Acetaminophen Fails to Improve Intact Survival in Preterm Infants: Lessons from the TREOCAPA Trial
Posted inCardiology news Pediatrics

Prophylactic Acetaminophen Fails to Improve Intact Survival in Preterm Infants: Lessons from the TREOCAPA Trial

Posted by MedXY By MedXY 02/20/2026
The TREOCAPA randomized clinical trial demonstrates that while prophylactic intravenous acetaminophen effectively promotes patent ductus arteriosus closure in extremely preterm infants, it does not significantly increase survival without severe neonatal morbidities at 36 weeks' postmenstrual age.
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Expectant Management Improves Early Survival Without Increasing BPD: Results from the PDA Randomized Clinical Trial
Posted inCardiology news Pediatrics

Expectant Management Improves Early Survival Without Increasing BPD: Results from the PDA Randomized Clinical Trial

Posted by MedXY By MedXY 12/12/2025
In extremely preterm infants with a protocol-defined PDA, expectant management yielded similar rates of death or BPD at 36 weeks’ postmenstrual age but significantly higher survival compared with active pharmacologic closure.
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