Early Uptake of Broad-Spectrum Antibiotic Prophylaxis in Pancreatoduodenectomy: Translating Trial Evidence into Practice
Posted inGeneral Surgery Infectious Diseases news

Early Uptake of Broad-Spectrum Antibiotic Prophylaxis in Pancreatoduodenectomy: Translating Trial Evidence into Practice

Following pivotal trial data demonstrating reduced infection and pancreatic fistula rates with piperacillin-tazobactam prophylaxis in pancreatoduodenectomy, adoption of broad-spectrum antibiotics increased significantly, particularly among patients with biliary stents, though racial disparities in use persisted.
Minimally Invasive Pancreatoduodenectomy Is Noninferior to Open Surgery for 90‑Day Complications but Raises Important Safety and Generalizability Questions
Posted inGeneral Surgery news Oncology

Minimally Invasive Pancreatoduodenectomy Is Noninferior to Open Surgery for 90‑Day Complications but Raises Important Safety and Generalizability Questions

An international randomized trial found minimally invasive pancreatoduodenectomy (mostly robotic) noninferior to open surgery for 90‑day overall complications and modestly faster functional recovery, with lower fistula and wound‑infection rates but a numerically higher 90‑day mortality.