Posted inGastroenterology news Oncology
MTFP1 and Metabolic Reprogramming: Unlocking New Targets in Pancreatic Cancer Liver Metastasis
MTFP1 promotes pancreatic ductal adenocarcinoma liver metastasis by enhancing mitochondrial oxidative phosphorylation via the ROS/PI3K/AKT/c-MYC/SLC1A5 axis, revealing a promising therapeutic target to reverse tumor immune suppression and reduce metastatic colonization.