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midostaurin

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老年新诊断AML患者中米哚妥林联合低剂量阿糖胞苷与维奈克拉:INTERVENE II期试验的证据与启示
Posted inClinical Updates Hematology-Oncology news

Combining Midostaurin with Low-Dose Cytarabine and Venetoclax in Older Adults with Newly Diagnosed AML: Evidence and Implications from the INTERVENE Phase 2 Trial

Posted by By MedXY 10/25/2026
The INTERVENE trial reveals that adding midostaurin to low-dose cytarabine and venetoclax is tolerable and improves FLT3-ITD clearance and survival in older AML patients with FLT3-ITD, addressing resistance in this high-risk subgroup.
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KIT 抑制剂治疗晚期全身性肥大细胞增多症的结局预测:来自基因与实验室动态监测的启示
Posted inHematology-Oncology news

Predicting Outcomes in Advanced Systemic Mastocytosis with KIT Inhibitors: Insights from Genetic and Laboratory Monitoring

Posted by By MedXY 10/23/2026
This article reviews how genetic profiling and dynamic laboratory markers predict clinical outcomes in advanced systemic mastocytosis treated with KIT inhibitors avapritinib and midostaurin, facilitating optimized treatment strategies.
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