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HEG1

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Shear Stress-Induced Endothelial HEG1 Signalling: A Novel Pathway Linking Blood Flow to Blood Pressure Regulation
Posted inCardiology news

Shear Stress-Induced Endothelial HEG1 Signalling: A Novel Pathway Linking Blood Flow to Blood Pressure Regulation

Posted by MedXY By MedXY 04/17/2026
Researchers identify HEG1 as a critical flow-sensitive endothelial protein that regulates blood pressure through CUL3-mediated degradation of PHACTR1, linking reduced shear stress in hypertension to impaired NO production and vascular dysfunction.
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