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Enlarged Perivascular Spaces as Early Neurovascular Biomarkers in Alzheimer Disease: Integrating Serum and MRI Findings from Multicultural Cohorts
Enlarged perivascular spaces (EPVS) correlate with serum biomarkers of neuroinflammation and amyloid pathology and associate with cognitive impairment, supporting their role as early MRI markers for Alzheimer disease (AD) vascular contributions and pathology.