Decoding Post-CD7 CAR-T EBV-Positive Lymphoproliferative Disorder: Insights from Multi-Omics and Spatial Profiling
This article explores how CD7 CAR-T therapy leads to EBV-positive lymphoproliferative disorder by revealing CD7-negative T cell dysfunction, immunosuppressive macrophage niches, and EBV-driven B cell transformation through multi-omic technologies.