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Diabetic kidney disease

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SGLT2 Inhibitors Edge Out GLP-1 RAs in Kidney Protection: Insights from a Target Trial Emulation
Posted inDiabetes & Endocrinology Nephrology news

SGLT2 Inhibitors Edge Out GLP-1 RAs in Kidney Protection: Insights from a Target Trial Emulation

Posted by By MedXY 01/26/2026
A nationwide Danish study suggests SGLT2 inhibitors offer superior protection against chronic kidney disease and acute kidney injury compared to GLP-1 receptor agonists in patients with type 2 diabetes, particularly for primary prevention.
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PAD4, NETs, and Inflammasome Activation: A New Mechanistic Link Between Diabetes and Cardiorenal Injury
Posted inCardiology Nephrology news

PAD4, NETs, and Inflammasome Activation: A New Mechanistic Link Between Diabetes and Cardiorenal Injury

Posted by By MedXY 11/28/2025
A translational study links hyperglycaemia-driven PAD4-dependent neutrophil extracellular trap (NET) formation and inflammasome activation to cardiac and renal inflammation, fibrosis, and heart failure in experimental diabetes—suggesting novel therapeutic targets.
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