Posted inCardiology Hematology-Oncology news
Impact of Germline and Somatic DNMT3A Variants on Pulmonary Arterial Hypertension: A New Frontier in Biomarkers and Therapeutics
Germline and somatic variants in DNMT3A and other CHIP genes elevate pulmonary arterial hypertension risk, including connective tissue disease-associated forms, through pro-inflammatory pathways, highlighting novel biomarkers and therapeutic targets.