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autoimmune hepatitis

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Zetomipzomib Shows Promise in Difficult-to-Treat Autoimmune Hepatitis: Insights from the Phase 2a PORTOLA Study
Posted inAllergy & Immunology Gastroenterology news

Zetomipzomib Shows Promise in Difficult-to-Treat Autoimmune Hepatitis: Insights from the Phase 2a PORTOLA Study

Posted by By MedXY 09/25/2026
The PORTOLA phase 2a trial evaluates zetomipzomib, a selective immunoproteasome inhibitor, demonstrating numerically improved biochemical remission and steroid-sparing effects in autoimmune hepatitis patients with inadequate response to standard treatments.
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PBC-AIH Variant: New International Consensus Clarifies Diagnosis and Treatment
Posted inGastroenterology news

PBC-AIH Variant: New International Consensus Clarifies Diagnosis and Treatment

Posted by By MedXY 05/18/2026
An international Delphi panel has standardized how to define, diagnose, and treat the PBC-AIH variant, emphasizing liver biopsy, periodic reassessment, and tailored immunosuppression for worse-risk patients.
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