Evaluating the Cost-Effectiveness of Early In-Bed Cycling Plus Routine Physiotherapy in Mechanically Ventilated ICU Patients: Insights from the CYCLE Trial
Posted inCritical Care news Rehabilitation Medicine Respiratory

Evaluating the Cost-Effectiveness of Early In-Bed Cycling Plus Routine Physiotherapy in Mechanically Ventilated ICU Patients: Insights from the CYCLE Trial

This economic evaluation from the CYCLE randomized trial found no significant cost or quality-adjusted life-year benefit by adding early in-bed cycling to usual physiotherapy for ICU patients on mechanical ventilation, underscoring a need for further research to clarify its value.
Impact of Epstein-Barr Virus Serology on Oral HPV Infection Dynamics in Early Childhood: Insights from the Finnish Family HPV Cohort
Posted inDentistry Infectious Diseases news Pathology & Lab Medicine Pediatrics

Impact of Epstein-Barr Virus Serology on Oral HPV Infection Dynamics in Early Childhood: Insights from the Finnish Family HPV Cohort

This study explores how early Epstein-Barr virus (EBV) infection and immune responses influence oral human papillomavirus (HPV) infections in children, revealing the interplay between EBV serology, paternal education, and oral HPV acquisition and clearance during the first three years of life.
Simultaneous Liver Transplant and Sleeve Gastrectomy: A Dual Approach to Combat Obesity and MASLD with Durable Outcomes
Posted inGastroenterology General Surgery news Transplantation

Simultaneous Liver Transplant and Sleeve Gastrectomy: A Dual Approach to Combat Obesity and MASLD with Durable Outcomes

Combining liver transplant with sleeve gastrectomy yields sustained weight loss, improved metabolic syndrome, and reduced liver allograft steatosis, without increasing mortality or graft loss, offering an effective treatment for obese patients with metabolic dysfunction-associated steatotic liver disease.
Optimizing Gonorrhea and Chlamydia Screening for Adolescents in Emergency Departments: Evidence from Targeted and Universal Strategies
Posted inClinical Updates Emergency Medicine Infectious Diseases news Pediatrics Public Health

Optimizing Gonorrhea and Chlamydia Screening for Adolescents in Emergency Departments: Evidence from Targeted and Universal Strategies

Comparative effectiveness evidence from multicenter pediatric emergency departments demonstrates that targeted and universally offered gonorrhea and chlamydia screening increase detection rates versus usual care, highlighting the need for integrated ED screening protocols in adolescents.