Specialties – Page 21

$Bailout Catheter Ablation: A Lifesaving Strategy for Refractory Ventricular Tachycardia in Early Acute Myocardial Infarction$

Bailout Catheter Ablation: A Lifesaving Strategy for Refractory Ventricular Tachycardia in Early Acute Myocardial Infarction

By MedXY 01/03/2026

A clinical study demonstrates that catheter ablation is a highly effective rescue therapy for refractory, scar-related ventricular tachycardia occurring in the early phase of acute myocardial infarction, challenging traditional management timelines.

Cardiology news

Beyond Arrhythmia: High-Risk Genotypes in Dilated Cardiomyopathy Predict Progression to Advanced Heart Failure

By MedXY 01/03/2026

A landmark Spanish study reveals that patients with 'arrhythmic' genotypes in dilated cardiomyopathy face a significantly higher risk of advanced heart failure events, including heart transplantation and VAD implantation, necessitating a paradigm shift in clinical management.

Cardiology news Pediatrics

Why Universal Cholesterol Screening for Familial Hypercholesterolaemia Should Wait Until Age One

By MedXY 01/03/2026

A landmark Norwegian study reveals that umbilical cord LDL-C levels overlap significantly between FH and non-FH newborns, making birth screening unreliable. In contrast, LDL-C becomes highly discriminative after age one, suggesting that universal screening should be deferred to early childhood.

Cardiology Emergency Medicine news

The Price of Time: 20-Year Study Reveals Pre-Hospital Delay as a Critical Driver of STEMI Mortality

By MedXY 01/03/2026

A 20-year analysis of 89,155 patients from the SWEDEHEART registry confirms that pre-hospital delay independently predicts short- and long-term mortality. Despite advances in reperfusion, women, elderly patients, and those with diabetes consistently experience significantly longer delays, highlighting a critical need for targeted public health interventions.

Cardiology news Radiology

Why the Parasternal Window May Be the New Gold Standard for Aortic Regurgitation Quantitation

By MedXY 01/03/2026

A landmark study demonstrates that measuring flow convergence from the parasternal long-axis window significantly outperforms apical PISA in feasibility and matches Cardiac MRI accuracy for assessing aortic regurgitation severity.

Cardiology news

JCAD Predicts Adverse Cardiovascular Events in ACS Patients with High Residual Risk

By MedXY 01/03/2026

A breakthrough study identifies the junctional protein associated with coronary artery disease (JCAD) as a significant predictor of recurrent cardiovascular events in ACS patients, particularly those with residual lipid and inflammatory risk, by modulating coagulation and fibrinolysis pathways.

Cardiology news

Beyond the Resting State: Why Exercise Pulmonary Vascular Resistance is the New Gold Standard for Fontan Prognosis

By MedXY 01/03/2026

Groundbreaking research demonstrates that exercise-induced pulmonary vascular resistance, rather than resting measurements, is a critical predictor of mortality in Fontan patients, supported by new non-invasive diagnostic algorithms for clinical practice.

Cardiology Critical Care news

The PERT Revolution: Rising Catheter-Directed Therapy Adoption Correlates with Improved Pulmonary Embolism Outcomes

By MedXY 01/02/2026

A multicenter registry study reveals that Pulmonary Embolism Response Teams (PERT) are increasingly utilizing catheter-directed therapies, particularly mechanical thrombectomy, leading to significantly lower in-hospital mortality and shorter hospital stays compared to national averages.

Cardiology Critical Care news

Restoring the Beat: How ERRγ Agonism Reverses Cardiomyocyte Subtype Conversion in Sepsis-Induced Cardiomyopathy

By MedXY 01/02/2026

This study identifies oestrogen-related receptor γ (ERRγ) as a master regulator of cardiomyocyte phenotypic transitions during sepsis, offering a novel therapeutic target to restore cardiac function and improve survival in sepsis-induced cardiomyopathy.

Clinical Updates Emergency Medicine news Respiratory

Awake Prone Positioning in COVID-19 Respiratory Failure: A Synthesis of Clinical Trial Evidence and the PROVID Study

By MedXY 01/02/2026

This review synthesizes the findings of the PROVID randomized clinical trial and broader literature, demonstrating that awake prone positioning (APP) significantly reduces the probability of intubation and death in patients with COVID-19 hypoxemic respiratory failure.

Cardiology Internal Medicine news

Oral Magnesium Reduces Risk of Death and Hospitalization in Heart Failure Patients with Hypomagnesemia

By MedXY 01/02/2026

A large-scale study of US veterans demonstrates that oral magnesium therapy significantly improves outcomes in heart failure patients with hypomagnesemia, especially those with levels below 1.3 mg/dL. Conversely, supplementation in normomagnesemic patients may increase risks, highlighting the necessity of baseline-guided clinical intervention.

Cardiology Neurology news

Beyond Stenosis: Wall Shear Stress and Oscillatory Index Emerge as Key Biomarkers for High-Risk Carotid Plaques

By MedXY 01/02/2026

A study in Eur Heart J Cardiovasc Imaging identifies elevated systolic wall shear stress and low oscillatory shear index as independent predictors of complicated carotid artery plaques, offering a more precise framework for stroke risk stratification than traditional luminal narrowing assessments.

Cardiology Neurology news

DKK2 Inhibition: A Novel Neurovascular Strategy to Salvage the Ischaemic Penumbra and Protect the Blood-Brain Barrier

By MedXY 01/02/2026

New research published in the European Heart Journal identifies Dickkopf-related protein 2 (DKK2) as a primary driver of neurovascular injury post-stroke. By suppressing Wnt signalling, DKK2 exacerbates neuronal death and blood-brain barrier breakdown, marking it as a high-priority therapeutic target.

Cardiology Internal Medicine news

Guided Antiplatelet De-escalation Proves Safe in High Atherothrombotic Risk ACS Patients: Insights from TROPICAL-ACS

By MedXY 01/02/2026

Post-hoc analysis of the TROPICAL-ACS trial demonstrates that platelet function testing-guided de-escalation of dual antiplatelet therapy from prasugrel to clopidogrel is safe and effective in ACS patients, regardless of their atherothrombotic risk profile, offering a viable strategy for individualized care.

Neurology news Radiology

Circumferential Aneurysm Wall Enhancement Predicts a Three-Fold Increase in 4-Year Risk of Instability

By MedXY 01/02/2026

A large-scale prospective study in JAMA Neurology identifies circumferential aneurysm wall enhancement (AWE) as a potent independent predictor of intracranial aneurysm growth or rupture, offering a critical radiological biomarker for clinical risk stratification.

Neurology news Public Health

Beyond the Lungs: How Ambient Air Pollution Drives Alzheimer’s Neuropathology and Cognitive Decline

By MedXY 01/02/2026

Emerging evidence confirms that air pollution, particularly PM2.5 and NO2, is directly associated with Alzheimer’s neuropathology, structural brain changes, and cognitive decline. New research highlights that these effects are partially mediated by pulmonary function and manifest as increased amyloid-related pathology at autopsy.

Clinical Updates Neurology news Pathology & Lab Medicine

Precision Screening for Preclinical Alzheimer Disease: The Ascendance of Plasma p-tau217 as a Scalable Biomarker

By MedXY 01/02/2026

This review synthesizes recent high-impact evidence on plasma p-tau217, demonstrating its superior utility in identifying amyloid pathology, predicting cognitive decline, and optimizing recruitment for primary prevention trials in cognitively unimpaired individuals.

Neurology news Psychiatry

A Global Standard: Understanding the New VasCog-2-WSO Criteria for Vascular Dementia

By MedXY 01/02/2026

Experts have released the VasCog-2-WSO criteria, an updated international standard for diagnosing vascular cognitive impairment and dementia. This revision introduces a preclinical stage and incorporates modern neuroimaging and fluid biomarkers to improve diagnostic consistency across global clinical and research settings.

Neurology news Respiratory

Early CPAP Intervention May Mitigate Parkinson Disease Risk in Patients with Obstructive Sleep Apnea

By MedXY 01/02/2026

A massive cohort study of 11.3 million US veterans reveals that obstructive sleep apnea is an independent risk factor for Parkinson disease, but early treatment with CPAP significantly reduces this risk, particularly in women.

Infectious Diseases Neurology news

Beyond the Fever: Acute Dengue Infection Linked to Significant Neurological Risks in Older Adults

By MedXY 01/02/2026

A large-scale population-based study in Singapore reveals that acute dengue virus infection is associated with a nearly ten-fold increase in neurological events, including memory loss and movement disorders, particularly in older adults and during specific serotype outbreaks.