Research reveals how psychedelics modulate immune-to-brain communication to reduce fear, offering new therapeutic avenues for stress-related psychiatric disorders.
A new meta-analysis finds that the average time from dementia symptom onset to diagnosis is 3.5 years, with even longer delays in younger patients and those with frontotemporal dementia.
A randomized clinical trial demonstrates that an Acceptance and Commitment Therapy-based parenting program reduces health care use, improves asthma control, and alleviates ADHD symptoms in children with both conditions.
ROC plus behavioral weight loss outperformed CBT in reducing binge eating among veterans, with transient advantages in weight loss. Long-term weight outcomes require further research.
Research links insufficient sleep and late bedtimes to higher risks of central precocious puberty in girls, with notable sleep issues appearing years before puberty onset.
Emerging research reveals a compelling connection between common herpes viruses and dementia risk, with vaccination and antiviral treatments showing promise for prevention.
Emerging research reveals a compelling connection between common herpes viruses and dementia risk, with vaccination and antiviral treatments showing promise for prevention.
A Canadian multisite trial demonstrated that the Walk 'n Watch structured exercise protocol significantly improves walking endurance in subacute stroke patients during inpatient rehabilitation without increasing serious adverse events.
Neuropsychiatric symptoms such as decreased motivation and emotional dysregulation significantly impair daily functioning in older adults without cognitive impairment, highlighting the need for early identification and intervention.
Recent data reveal that transfeminine adults experience significantly higher prevalence of Alzheimer's disease and related dementias compared to matched cisgender peers, independent of gender-affirming hormone therapy, highlighting urgent needs for targeted research and care strategies.
A landmark UK Biobank study demonstrates that elevated lipoprotein(a) independently predicts both the onset and progression of peripheral artery disease and carotid stenosis, beyond traditional cardiovascular risk factors.
Three major Chinese trials examine intravenous and intra-arterial tenecteplase as adjuncts to thrombectomy in acute large-vessel occlusion stroke, revealing functional benefit with intravenous use before thrombectomy but not after reperfusion.
A study from the Framingham Heart Study cohort reveals that traumatic brain injury (TBI) is linked to significant brain volume loss in older women but not men, highlighting sex-specific vulnerability to neurodegeneration post-TBI.
The ANGEL-TNK trial found that intra-arterial tenecteplase after successful endovascular thrombectomy improved excellent neurological outcomes at 90 days without increasing bleeding or mortality, but secondary outcomes showed no significant benefit.
Recent studies confirm that both childhood and adult lead exposure, especially from gasoline and industrial sources, are associated with increased risk for cognitive decline and dementia in later life.
Regular walking and lifestyle interventions slow cognitive decline, especially in APOE ε4 carriers at heightened Alzheimer’s risk, with effects pronounced in women. Evidence underscores the value of simple activity and healthy diet for at-risk older adults.
A large US trial shows that intensive, structured lifestyle programs yield greater cognitive improvement in at-risk older adults compared to self-guided approaches, though both are beneficial.
Community-based data suggest lecanemab is safe and effective for early-stage Alzheimer’s, with manageable ARIA rates and infusion reactions, particularly in ApoE4 noncarriers.