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Comparative Efficacy and Safety of Treatments for Moderate to Severe Hidradenitis Suppurativa: Insights from a Living Network Meta-Analysis
Posted inDermatology news

Comparative Efficacy and Safety of Treatments for Moderate to Severe Hidradenitis Suppurativa: Insights from a Living Network Meta-Analysis

Posted by By MedXY 10/27/2025
This living systematic review and network meta-analysis evaluates efficacy, safety, and tolerability of medical treatments for moderate to severe hidradenitis suppurativa, highlighting top-performing agents and informing clinical decision-making.
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Oral Manifestations of Lamellar Ichthyosis: A Case Report of Two Siblings
Posted inDermatology news Pediatrics

Oral Manifestations of Lamellar Ichthyosis: A Case Report of Two Siblings

Posted by By MedXY 10/25/2025
Two brothers with lamellar ichthyosis presented with enamel defects and dental caries; dental rehabilitation with preventive measures was completed alongside dermatologic care.
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Optimizing Scar Healing Post-Dermatologic Surgery: A Comparative Look at Hydrocolloid Dressings and Petroleum Ointments
Posted inDermatology news Plastic Surgery

Optimizing Scar Healing Post-Dermatologic Surgery: A Comparative Look at Hydrocolloid Dressings and Petroleum Ointments

Posted by By MedXY 10/25/2025
This study evaluates whether a single application of hydrocolloid dressing improves scar appearance and reduces complications compared to daily petroleum ointment after dermatologic excisions.
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Nine-Year Outcomes of Nivolumab vs Ipilimumab in Resected Stage III/IV Melanoma: Sustained Survival Benefit and Safety
Posted inDermatology Oncology

Nine-Year Outcomes of Nivolumab vs Ipilimumab in Resected Stage III/IV Melanoma: Sustained Survival Benefit and Safety

Posted by By MedXY 10/25/2025
The 9-year follow-up of the CheckMate 238 trial confirms that nivolumab offers longer recurrence-free survival than ipilimumab in resected stage III/IV melanoma, with durable safety and favorable distant metastasis-free survival.
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Enhancing Surgical Outcomes: Hydrocolloid Dressings vs Petroleum Ointment for Scar Management
Posted inDermatology news Plastic Surgery

Enhancing Surgical Outcomes: Hydrocolloid Dressings vs Petroleum Ointment for Scar Management

Posted by By MedXY 10/24/2025
This clinical trial compares the effectiveness and safety of hydrocolloid dressings versus petroleum ointment in post-surgical scar healing, emphasizing patient comfort and cosmetic outcomes.
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T-Cell Receptor Clonotypes as Prognostic Markers in Cutaneous T-Cell Lymphoma: Insights from Next-Generation Sequencing
Posted inDermatology Hematology-Oncology news

T-Cell Receptor Clonotypes as Prognostic Markers in Cutaneous T-Cell Lymphoma: Insights from Next-Generation Sequencing

Posted by By MedXY 10/24/2025
This study identifies specific T-cell receptor clonotypes associated with aggressive subtypes and poorer survival in mycosis fungoides and Sézary syndrome, supporting TCR sequencing as a tool for refined risk stratification in cutaneous T-cell lymphoma.
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Baricitinib Shows Promising Results in Restoring Hair Growth in Adolescents with Severe Alopecia Areata: Phase 3 BRAVE-AA-PEDS Trial
Posted inDermatology Pediatrics

Baricitinib Shows Promising Results in Restoring Hair Growth in Adolescents with Severe Alopecia Areata: Phase 3 BRAVE-AA-PEDS Trial

Posted by By MedXY 10/24/2025
The phase 3 BRAVE-AA-PEDS trial demonstrates that baricitinib, a JAK inhibitor, significantly restores scalp, eyebrow, and eyelash hair in adolescents with severe alopecia areata, achieving up to 80% hair regrowth in recent-onset cases after one year of treatment.
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Refining Sentinel Lymph Node Biopsy Decisions in Melanoma: Insights from the MERLIN_001 Gene Expression Profiling Study
Posted inDermatology General Surgery Oncology

Refining Sentinel Lymph Node Biopsy Decisions in Melanoma: Insights from the MERLIN_001 Gene Expression Profiling Study

Posted by By MedXY 10/24/2025
The MERLIN_001 study validates a combined clinicopathological and gene expression profile test that accurately predicts sentinel lymph node metastasis risk in patients with cutaneous melanoma, potentially guiding safer, more personalized surgical decisions.
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Evolving Dermatologic Landscape in HIV: Prevalence, Incidence, and Risk Factors in the Modern ART Era from the DC Cohort
Posted inDermatology HIV/AIDS Specialties

Evolving Dermatologic Landscape in HIV: Prevalence, Incidence, and Risk Factors in the Modern ART Era from the DC Cohort

Posted by By MedXY 10/22/2025
Despite advances in antiretroviral therapy, dermatologic diseases remain prevalent in people with HIV, with incidence declining yet significant disparities persisting related to immune status, demographics, and structural factors.
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Enhancing Skin Cancer Surveillance in Solid Organ Transplant Recipients: Impact of the KP-SUNTRAC Risk-Based Program
Posted inDermatology Nephrology news

Enhancing Skin Cancer Surveillance in Solid Organ Transplant Recipients: Impact of the KP-SUNTRAC Risk-Based Program

Posted by By MedXY 10/15/2025
A retrospective cohort study demonstrates that implementation of KP-SUNTRAC increases targeted skin cancer screening and detection among high-risk solid organ transplant recipients without increasing health care utilization.
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Prognostic Markers and Survival Outcomes in Advanced Mycosis Fungoides and Sézary Syndrome: Insights from the Cutaneous Lymphoma International Consortium
Posted inDermatology Hematology-Oncology news

Prognostic Markers and Survival Outcomes in Advanced Mycosis Fungoides and Sézary Syndrome: Insights from the Cutaneous Lymphoma International Consortium

Posted by By MedXY 10/14/2025
A large international study identified key prognostic markers affecting survival in advanced-stage mycosis fungoides and Sézary syndrome, enabling risk stratification and guiding clinical management.
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Large-Cell Transformation of Mycosis Fungoides: Clinical Patterns, Prognostic Insights, and Implications for Staging
Posted inDermatology Hematology-Oncology news

Large-Cell Transformation of Mycosis Fungoides: Clinical Patterns, Prognostic Insights, and Implications for Staging

Posted by By MedXY 10/14/2025
Large-cell transformation in mycosis fungoides marks an aggressive disease subset with distinct prognostic groups and poor survival, highlighting the need for tailored treatment and integration into staging systems.
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CLIPI: A New Prognostic Index Transforming Risk Stratification in Advanced Cutaneous Lymphomas
Posted inDermatology Hematology-Oncology news

CLIPI: A New Prognostic Index Transforming Risk Stratification in Advanced Cutaneous Lymphomas

Posted by By MedXY 10/14/2025
The CLIPI prognostic index refines risk stratification in advanced mycosis fungoides and Sézary syndrome, identifying distinct survival groups to guide personalized treatment decisions and improve outcomes.
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Once-Daily Oral Icotrokinra vs Placebo and Deucravacitinib in Moderate-to-Severe Plaque Psoriasis: Insights from ICONIC-ADVANCE 1 & 2 Phase 3 Trials
Posted inClinical Updates Dermatology news Specialties

Once-Daily Oral Icotrokinra vs Placebo and Deucravacitinib in Moderate-to-Severe Plaque Psoriasis: Insights from ICONIC-ADVANCE 1 & 2 Phase 3 Trials

Posted by By MedXY 10/10/2025
ICONIC-ADVANCE 1 & 2 phase 3 trials demonstrate that once-daily oral icotrokinra significantly improves skin clearance with superior efficacy and favorable safety compared to placebo and deucravacitinib in moderate-to-severe plaque psoriasis.
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IL23R Polymorphism as a Genetic Predictor of Paradoxical Psoriasis in Anti-TNFα-Treated IBD Patients
Posted inDermatology Gastroenterology

IL23R Polymorphism as a Genetic Predictor of Paradoxical Psoriasis in Anti-TNFα-Treated IBD Patients

Posted by By MedXY 10/09/2025
The IL23R1142G>A genetic variant strongly predicts paradoxical psoriasis in inflammatory bowel disease patients undergoing anti-TNFα therapy, guiding personalized treatment decisions.
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Patient-Centered Insights: Understanding Treatment Preferences in Chronic Urticaria Management
Posted inAllergy & Immunology Dermatology news

Patient-Centered Insights: Understanding Treatment Preferences in Chronic Urticaria Management

Posted by By MedXY 10/08/2025
This systematic review highlights patient and caregiver priorities in chronic urticaria treatment, emphasizing rapid symptom relief, long-term effectiveness, and safety.
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Transcutaneous Auricular Vagus Nerve Stimulation: A Promising New Therapy for Erythematotelangiectatic Rosacea
Posted inDermatology Neurology news

Transcutaneous Auricular Vagus Nerve Stimulation: A Promising New Therapy for Erythematotelangiectatic Rosacea

Posted by By MedXY 10/08/2025
A randomized trial demonstrates that 3 weeks of transcutaneous auricular vagus nerve stimulation significantly reduces facial erythema, flushing, and associated neuropsychiatric symptoms in erythematotelangiectatic rosacea, with effects persisting 24 weeks post-treatment.
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Harnessing Artificial Intelligence for Diagnosing Sexually Transmitted Infections and Anogenital Dermatoses: Insights from a Systematic Review and Meta-Analysis
Posted inAI Dermatology Infectious Diseases news Specialties

Harnessing Artificial Intelligence for Diagnosing Sexually Transmitted Infections and Anogenital Dermatoses: Insights from a Systematic Review and Meta-Analysis

Posted by By MedXY 10/04/2025
AI demonstrates high accuracy in identifying mpox and other anogenital conditions from clinical images, yet significant research gaps and validation needs remain before clinical adoption.
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Australian Dermatologists’ Perspectives on AI Integration: Trust, Benefits, and Barriers in Clinical Practice
Posted inClinical Updates Dermatology news

Australian Dermatologists’ Perspectives on AI Integration: Trust, Benefits, and Barriers in Clinical Practice

Posted by By MedXY 09/28/2025
A recent survey reveals that Australian dermatologists are cautiously integrating AI into practice, prioritizing accuracy and trust for diagnostic use, with optimism about AI enhancing patient access and reducing workload but concerns about data transparency and corporate influence.
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Mediterranean Diet as Adjunct Therapy in Psoriasis: Insights from the MEDIPSO Randomized Clinical Trial
Posted inDermatology Family Medicine & Nutrition Specialties

Mediterranean Diet as Adjunct Therapy in Psoriasis: Insights from the MEDIPSO Randomized Clinical Trial

Posted by By MedXY 09/28/2025
A 16-week Mediterranean diet intervention significantly reduced psoriasis severity and improved metabolic markers in patients with mild to moderate disease, suggesting diet’s role as adjunctive therapy in psoriasis management.
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  • Pretransfer IV Thrombolysis in Basilar Artery Occlusion: Improved Recanalization and 3‑Month Outcomes Without Clear Safety Signals
  • Giving IV Thrombolysis in the Late Window Before Transfer for Thrombectomy: Improved Recanalization and 3‑Month Outcomes in a Multicenter French Cohort
  • Low-Dose Interleukin-2 as Adjunct to Riluzole in ALS: Insights from the Phase 2b MIROCALS Trial
  • Low-Dose Interleukin-2 Accelerates Disease Control and May Spare Steroids in Moderate-to-Severe Bullous Pemphigoid
  • Lorundrostat Lowers 24‑Hour Systolic Blood Pressure in Treatment‑Resistant Hypertension but Raises Hyperkalemia Concerns
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