Introduction
Mental fatigue, characterized by persistent tiredness and diminished cognitive functioning following prolonged cognitive effort, is recognized for its deleterious effects on both cognitive and physical performance. Particularly in athletic and occupational settings requiring sustained vigilance, mental fatigue compromises task execution and endurance capacity. Nutritional interventions, notably adaptogens such as Rhodiola Rosea (RR), have gained attention as potential modulators of fatigue and enhancers of physical and cognitive performance. RR, a herbal extract standardized for rosavins and salidrosides, is proposed to exert ergogenic and adaptogenic effects through modulation of the hypothalamic–pituitary–adrenal axis and catecholaminergic systems, which influence energy metabolism, neural excitability, and muscle contractility.
