Hypertensive adults with concurrent prediabetes and subclinical myocardial injury (hs-cTnI) or stress (NT-proBNP) face a four-to-fivefold increased risk of incident heart failure compared to those with normoglycemia and normal biomarker levels.
Longitudinal increases (≥25% over 12 months) in cardiac biomarkers in patients with prediabetes further compound the risk, suggesting that dynamic monitoring is clinically valuable.
The findings advocate for a shift in risk stratification, moving beyond blood pressure control to include glycemic status and biomarker profiling in the management of hypertensive populations.
The Hidden Intersection of Hypertension and Glycemic Dysregulation
