Evaluating the Role of Estrogen Replacement Therapy Combined with Resistance Exercise in Older Women with Knee Osteoarthritis: Insights from a Randomised Clinical Trial
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Evaluating the Role of Estrogen Replacement Therapy Combined with Resistance Exercise in Older Women with Knee Osteoarthritis: Insights from a Randomised Clinical Trial

This trial assessed the additive effects of low-dose transdermal estrogen replacement therapy combined with resistance exercise in women aged 65+ with knee osteoarthritis, finding no overall significant benefit but suggesting potential improvements in early-stage disease and mental health.
Silymarin in Clinical Medicine: A Decade of Therapeutic Advances and Future Disease Targets
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Silymarin in Clinical Medicine: A Decade of Therapeutic Advances and Future Disease Targets

Comprehensive review of recent decade research on silymarin elucidates its antioxidant, anti-inflammatory, and hepatoprotective effects, highlighting promising clinical applications in metabolic diseases, neurodegeneration, liver disorders, and inflammatory conditions, with emerging potential in oncology and dermatology.
Recent Advances in Astragalus membranaceus Research: Clinical Applications, Mechanistic Insights, and Future Therapeutic Potential
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Recent Advances in Astragalus membranaceus Research: Clinical Applications, Mechanistic Insights, and Future Therapeutic Potential

This review synthesizes the latest PubMed-indexed evidence on Astragalus membranaceus, highlighting its immunomodulatory, renal-protective, cardiovascular, and neuroprotective effects, its synergistic potential with conventional drugs, and prospective indications for chronic kidney disease, heart failure, diabetic complications, and cancer adjunctive therapy.
Recent Advances in Cinnamon and Its Extracts: Clinical Applications and Therapeutic Potentials Across Metabolic, Cardiovascular, Cognitive, and Infectious Diseases
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Recent Advances in Cinnamon and Its Extracts: Clinical Applications and Therapeutic Potentials Across Metabolic, Cardiovascular, Cognitive, and Infectious Diseases

A decade of research highlights cinnamon's benefits in glycemic control, lipid modulation, anti-inflammatory effects, cognitive enhancement, and antimicrobial activity, supporting its adjunctive clinical use and revealing promising therapeutic directions.