Medxy AI

Intra-arterial Tenecteplase After Thrombectomy for Acute Stroke: Interpreting the ANGEL-TNK Randomized Clinical Trial

By MedXY 07/31/2025

The ANGEL-TNK trial found that intra-arterial tenecteplase after successful endovascular thrombectomy improved excellent neurological outcomes at 90 days without increasing bleeding or mortality, but secondary outcomes showed no significant benefit.

Clinical Updates Wellness & Lifestyle

Dual IL-17A/F Blockade and Increased Candidiasis Risk

By MedXY 07/31/2025

Blocking both IL-17A and IL-17F impairs neutrophil migration, reducing antifungal defense and raising candidiasis risk in patients on bimekizumab, according to in vitro evidence.

Clinical Updates Wellness & Lifestyle

Inconsistent Bone Health Management in Older Women With Breast Cancer: Insights From the Age Gap Study

By MedXY 07/31/2025

Significant variation exists in bone health management for older women receiving endocrine therapy for breast cancer, highlighting the need for standardized care.

Clinical Updates

多発性筋痛症が死亡リスクの増加と関連しないこと：38年間のノルウェー集団研究からの洞察

By MedXY 07/31/2025

ノルウェー南部での38年間の前向き研究は、単独の多発性筋痛症（PMR）が対照群と比較して全原因による死亡リスクを増加させないことを示しています。男性ではさらに低い死亡リスクが見られました。

Clinical Updates Wellness & Lifestyle

Polymyalgia Rheumatica Not Associated with Increased Mortality: Insights from a 38-Year Norwegian Cohort Study

By MedXY 07/31/2025

A 38-year prospective study in Southern Norway demonstrates that isolated polymyalgia rheumatica (PMR) does not increase all-cause mortality compared to matched population controls, with men showing even lower mortality risk.

Clinical Updates Wellness & Lifestyle

ED Intubation in Active Hemorrhage Linked to Increased Mortality: Insights from a Nationwide Cohort Study

By MedXY 07/31/2025

Intubation in the emergency department for trauma patients with active hemorrhage is associated with higher mortality, more ICU admissions, and greater transfusion needs compared to intubation in the operating room.

Clinical Updates Wellness & Lifestyle

Veligrotug Emerges as a Promising Therapy for Thyroid Eye Disease: Insights from the THRIVE and THRIVE-2 Trials

By MedXY 07/31/2025

Veligrotug demonstrates robust efficacy and manageable safety in both active and chronic thyroid eye disease, positioning itself as a potential alternative to teprotumumab based on phase 3 THRIVE trial data.

Clinical Updates Wellness & Lifestyle

Inhaled Isoflurane: A Noninferior Alternative to Midazolam for Pediatric ICU Sedation

By MedXY 07/31/2025

A multicenter phase 3 trial finds inhaled isoflurane as effective as intravenous midazolam for sedation in mechanically ventilated children, with added benefits of reduced opioid use and faster extubation.

Wellness & Lifestyle

Sweetener Consumption and Genetic Predisposition: New Insights into Early Puberty Risk in Children

By Dr.Paul 07/31/2025

Sweetener intake, especially aspartame and sucralose, is linked to increased risk of early puberty in genetically predisposed children, with notable sex-specific differences

Intra-arterial Tenecteplase After Thrombectomy for Acute Stroke: Interpreting the ANGEL-TNK Randomized Clinical Trial

Dual IL-17A/F Blockade and Increased Candidiasis Risk

Inconsistent Bone Health Management in Older Women With Breast Cancer: Insights From the Age Gap Study

多発性筋痛症が死亡リスクの増加と関連しないこと：38年間のノルウェー集団研究からの洞察

Polymyalgia Rheumatica Not Associated with Increased Mortality: Insights from a 38-Year Norwegian Cohort Study

ED Intubation in Active Hemorrhage Linked to Increased Mortality: Insights from a Nationwide Cohort Study

Veligrotug Emerges as a Promising Therapy for Thyroid Eye Disease: Insights from the THRIVE and THRIVE-2 Trials

Inhaled Isoflurane: A Noninferior Alternative to Midazolam for Pediatric ICU Sedation

Sweetener Consumption and Genetic Predisposition: New Insights into Early Puberty Risk in Children

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