Mucosal Impedance: A Novel Diagnostic Tool for Refining GERD Phenotyping and Surgical Decision-Making

Background

Gastroesophageal reflux disease (GERD) remains a prevalent condition with significant morbidity and healthcare burden. Traditional diagnostic tools, such as endoscopy and ambulatory pH monitoring, have limitations in assessing mucosal integrity and predicting treatment response. Mucosal impedance (MI) emerges as a promising technique to address these gaps by directly measuring epithelial injury and barrier function.

Physiologic Rationale

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