Highlights
- The IRIS-MAIN registry provides robust, prospective, multicentre long-term data (>10 years follow-up) comparing PCI with drug-eluting stents versus CABG in patients with unprotected left main coronary artery disease across diverse Asian populations.
- No statistically significant difference in all-cause mortality was found between PCI and CABG after adjustment for baseline covariates, suggesting comparable long-term survival outcomes.
- Findings underscore the importance of a multidisciplinary Heart Team approach for personalized treatment decisions, integrating clinical, anatomic, and patient preference factors.
- Despite observational design, this large-scale real-world evidence complements prior randomized trials, contributing critical data on long-term comparative effectiveness.
Background
Specialty calculators
For clinical reference; use professional judgment.
