Highlight
– In the PISCES randomized, double-blind, placebo-controlled trial (n=1228), 4 g/day of fish oil (1.6 g EPA + 0.8 g DHA) reduced the rate of serious cardiovascular events in maintenance hemodialysis patients (HR 0.57; 95% CI 0.47–0.70; P<0.001).
– Broad benefit was observed across clinically important endpoints, including cardiac death (HR 0.55), myocardial infarction (HR 0.56), peripheral vascular disease leading to amputation (HR 0.57), and stroke (HR 0.37).
