Impact of Diabetes on the Triglyceride-Glucose Index and Cardiovascular Outcomes in Coronary Heart Disease: A Comprehensive Meta-Analysis

Highlight

  • Elevated triglyceride-glucose (TyG) index is associated with increased risk of major adverse cardiovascular events (MACEs) in patients with coronary heart disease (CHD), regardless of diabetes status.
  • The TyG index predicts all-cause mortality, nonfatal myocardial infarction, and revascularization in both diabetic and nondiabetic CHD populations.
  • Nonfatal stroke is significantly linked with TyG index only in diabetic CHD patients, not in those without diabetes.
  • This study supports the TyG index as a potential prognostic marker in CHD but highlights the need for further prospective validation.

Background

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