Traumatic Brain Injury (TBI) and depression were found to nearly triple the 10-year hazard of incident Alzheimer Disease and Related Dementias (ADRD).
Alcohol Use Disorder (AUD) remains a potent modifiable risk factor, doubling the risk of dementia in the aging Veteran cohort.
Military-specific environmental exposures, including Agent Orange and pyridostigmine bromide tablets, are significantly associated with increased ADRD incidence.
Findings from the Million Veteran Program (MVP) provide a high-resolution map for targeted screening and early intervention in high-risk Veteran populations.
Background: The Growing Burden of Dementia in the Veteran Population