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Cold Agglutinin Syndrome (CAS) often emerges around 10 days after the onset of Mycoplasma pneumoniae (MP) respiratory infection symptoms in adults. CAS is characterized by significant hemolytic anemia requiring frequent transfusions and is associated with high rates of intensive care unit (ICU) admissions and venous thromboembolic events (VTE). Despite these complications, 90% of patients recover, and glucocorticoid therapy does not significantly influence recovery outcomes.
