Clinical Updates – Page 11

Evaluating Diagnocat AI: Accuracy in Detecting Periapical Radiolucencies on CBCT Scans of Molars

By MedXY 09/14/2025

A study assessing the AI-based platform Diagnocat reveals high sensitivity but moderate specificity in detecting periapical radiolucencies on CBCT scans of non-root-filled molars, with decreased accuracy post-root treatment, underscoring the need for clinician oversight.

AI Clinical Updates General Surgery Specialties

Harnessing AI in Surgical Education: Deep Language Learning Model-Based Simulation Enhances Undergraduate History-Taking Skills

By MedXY 09/14/2025

A randomized controlled trial demonstrates that integrating deep language learning model (DLM) simulations into surgical training significantly improves history-taking skills and communication confidence among senior medical students.

AI Clinical Updates news Plastic Surgery Specialties

Enhancing Dental Diagnostics: The Role of AI Assistance in Detecting Periapical Radiolucencies

By MedXY 09/14/2025

A randomized controlled trial demonstrates that AI assistance moderately improves dentists' accuracy in diagnosing periapical radiolucencies, mainly by reducing false positives, with significant benefits for junior clinicians and a shift towards conservative treatment decisions.

Clinical Updates news

Enhancing Surgical History-Taking Skills in Medical Students Using AI-Driven Simulated Patients: A Randomized Controlled Trial

By MedXY 09/14/2025

This randomized trial shows that using a deep language learning model as a simulated patient significantly improves surgical history-taking skills and student confidence in senior medical students during clinical rotations.

Clinical Updates Gastroenterology Oncology Public Health Specialties

Optimizing Colorectal Cancer Screening Outreach for Adults Aged 45-49: Insights From a Large-Scale Randomized Trial

By MedXY 09/13/2025

A large UCLA Health randomized clinical trial found that usual care via mailed FIT outreach outperformed active choice strategies in colorectal cancer screening uptake among adults aged 45 to 49 years, highlighting the challenges in engaging younger populations in screening programs.

Clinical Updates Psychiatry

Accelerating Depression Recovery: The Impact of Measurement-Based Care in Pakistan’s Low-Resource Settings

By MedXY 09/13/2025

A randomized clinical trial in Pakistan demonstrates that measurement-based care accelerates antidepressant treatment response and remission in major depressive disorder compared to standard care, underscoring its potential in low-resource settings.

Clinical Updates news

Evaluating Peer Coaching for Weight Management in Primary Care: Insights from a VA-Based Cluster Randomized Clinical Trial

By MedXY 09/13/2025

A cluster randomized trial in veterans assessed peer coaching for weight management, showing improved program attendance but no significant 12-month weight loss difference versus enhanced usual care.

Clinical Updates news Psychiatry Specialties

Personalized High-Definition Transcranial Direct Current Stimulation: A Promising Rapid Intervention for Moderate to Severe Depression

By MedXY 09/13/2025

A randomized clinical trial demonstrates that personalized high-definition transcranial direct current stimulation (HD-tDCS) significantly improves mood in patients with moderate to severe depression, showing faster and comparable effect sizes to conventional therapies and also reducing anxiety symptoms.

Cardiology Clinical Updates Family Medicine & Nutrition Radiology Specialties

CT Angiography Enhances Lifestyle and Prevention Uptake in Cardiovascular Risk Management: Insights from SCOT-HEART 2 Substudy

By MedXY 09/13/2025

A nested substudy from SCOT-HEART 2 reveals coronary CT angiography modestly improves healthy lifestyle adherence, preventive therapy acceptance, and risk factor modification compared to traditional cardiovascular risk scoring in asymptomatic individuals at risk.

Clinical Updates General Surgery Oncology Radiology Specialties

Preoperative versus Postoperative Stereotactic Radiation Therapy for Brain Metastases: Safety, Feasibility, and Efficiency Insights from a Phase 3 Randomized Trial

By MedXY 09/13/2025

A phase 3 randomized trial demonstrates that preoperative stereotactic radiation therapy (SRT) for brain metastases offers comparable safety and reduced treatment duration compared to postoperative SRT, potentially improving patient care logistics.

Clinical Updates news Oncology Radiology Specialties

Induction vs Adjuvant Chemoradiotherapy in High-Risk N2-N3 Nasopharyngeal Carcinoma: Insights from a Phase 3 Randomized Trial

By MedXY 09/12/2025

This phase 3 trial compares induction-concurrent chemotherapy with concurrent-adjuvant chemotherapy in high-risk N2 to N3 nasopharyngeal carcinoma, finding no significant difference in 3-year progression-free survival while highlighting distinct safety profiles.

Anesthesiology Clinical Updates General Surgery news Specialties

Intercostal Nerve Block: A Viable Alternative to Thoracic Epidural for Pain Control in Lung Surgery

By MedXY 09/12/2025

This randomized trial demonstrates that single-shot intercostal nerve block offers noninferior pain relief compared to thoracic epidural analgesia after thoracoscopic lung resection, with benefits in opioid reduction, mobility, and shorter hospitalization.

Clinical Updates news Oncology Specialties

U-BOMB Phase 2 Trial: Promising Activity of Utidelone Plus Bevacizumab in ERBB2-Negative Metastatic Breast Cancer with Active Brain Metastases

By MedXY 09/12/2025

The U-BOMB phase 2 trial demonstrates that the combination of utidelone and bevacizumab shows encouraging efficacy and tolerability in patients with ERBB2-negative metastatic breast cancer and active brain metastases, addressing a critical unmet clinical need.

Clinical Updates Oncology Specialties

High-Dose Aumolertinib Demonstrates Promising Efficacy in Untreated EGFR-Mutant NSCLC with Brain Metastases: Insights from the ACHIEVE Phase 2 Trial

By MedXY 09/11/2025

The ACHIEVE Phase 2 trial reveals that high-dose aumolertinib offers significant intracranial and systemic control with a manageable safety profile in patients with untreated EGFR-mutant NSCLC and brain metastases, highlighting its therapeutic potential.

Clinical Updates news Ophthalmology Specialties

Diversified Segmental Defocus Optimization Lenses With and Without Atropine: A New Frontier in Myopia Prevention

By MedXY 09/11/2025

A recent randomized clinical trial demonstrates that diversified segmental defocus optimization (DSDO) spectacle lenses significantly reduce the onset and progression of myopia in children, with or without adjunct low-dose atropine.

Clinical Updates news Public Health Specialties

Impact of Physician-Personalized Videos and Infographics on Influenza Vaccination Rates: Findings from a Randomized Clinical Trial

By MedXY 09/11/2025

This trial assessed if videos and infographics from primary care physicians improve flu vaccination rates; overall effects were minimal, but notable improvements occurred in children.

Clinical Updates news OB/GYN & Women's Health Specialties

Metabolic Health in Pregnancy: Unveiling the Differential Impact of Prenatal Behavioral Interventions on Obesity Phenotypes

By MedXY 09/11/2025

This analysis reveals that metabolic health phenotypes, rather than gestational weight gain alone, significantly influence maternal and infant outcomes in prenatal behavioral interventions among obese pregnant women.

Clinical Updates Neurology news Specialties

Small Financial Incentives Boost Enrollment in Memory Study but Do Not Enhance Racial Diversity

By MedXY 09/11/2025

A randomized trial shows that guaranteed small financial rewards increase enrollment in an Alzheimer’s prevention registry among economically diverse older adults, whereas lottery prizes do not, with limited impact on racial and ethnic representation.

Clinical Updates Neurology Specialties

Optimizing Head Positioning in Large Vessel Occlusion Stroke Before Thrombectomy: Evidence from a Randomized Clinical Trial

By MedXY 09/11/2025

A recent randomized clinical trial demonstrates that 0° head-of-bed positioning prior to thrombectomy in patients with large vessel occlusion stroke preserves neurological stability and reduces mortality compared to the conventional 30° elevation.

Clinical Updates news OB/GYN & Women's Health Specialties

Enhancing Cervical Cancer Screening in Underserved Populations: Insights from the PRESTIS Randomized Clinical Trial

By MedXY 09/11/2025

The PRESTIS trial demonstrates that mailed self-collection kits significantly increase cervical cancer screening participation in a safety-net health system, with additional benefits from patient navigation support.