Is 2 Liters of PEG Necessary? Simplified Water Prep Proves Effective for Crohn’s Capsule Endoscopy

Highlights

  • A simplified preparation involving clear liquids and 1.5 L of water is non-inferior to standard 2 L PEG-based regimens for small bowel capsule endoscopy (SBCE) in Crohn’s disease.
  • Intestinal cleanliness, diagnostic yield, and capsule completion rates were comparable between the simplified and PEG-based groups.
  • Patient acceptability and procedural comfort were significantly higher in the simplified preparation group.
  • The KODA score demonstrated high diagnostic accuracy (80%) for discriminating intestinal cleanliness levels.

Background: The Challenge of Bowel Preparation in Crohn’s Disease

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