Recent research indicates that patients with type 2 diabetes who use SGLT2 inhibitors after a urinary tract infection have a lower mortality risk compared to those using DPP-4 inhibitors.
Oracle Health unveils a next-generation AI-powered, voice-first electronic health record (EHR) system designed from the ground up to improve clinical workflow and challenge Epic’s market dominance in the U.S. acute care sector.
Explore how AI is revolutionizing healthcare by enhancing diagnostics, predicting diseases, and supporting medical professionals in various capacities.
The integration of AI in colonoscopy improves adenoma detection but raises concerns about declining physician skills when AI support is withdrawn, highlighting a potential clinical 'de-skilling' effect.
Linea integrates generative AI and high-touch virtual nursing to proactively manage heart failure patients, achieving a 50% reduction in hospital readmissions within 90 days, substantially lowering costs and improving patient outcomes.
A comprehensive survey of 233 US healthcare systems reveals widespread AI deployment with key barriers including cost and resource limitations; highlights the critical role of CFOs and CIOs in AI decision-making and the growing influence of integrated EHR systems.
Illinois has enacted legislation banning AI chatbots for mental health therapy, joining Utah and Nevada in addressing concerns over AI's impact on vulnerable populations.
A randomized trial demonstrates that non-invasive transcutaneous vagus nerve stimulation improves peak oxygen uptake and exercise performance in healthy volunteers, highlighting its potential as a safe and scalable method to boost cardiorespiratory fitness.
In patients with heart failure and reduced ejection fraction, anaemia predicts iron homeostasis disruption and influences response to empagliflozin, which increases myocardial iron and improves cardiac function and exercise capacity.
A multicenter randomized trial demonstrates that delayed remote ischemic preconditioning 24 hours prior to coronary angiography or PCI significantly lowers the incidence of contrast-associated acute kidney injury in high-risk patients.
The ASCOT-Legacy study shows atorvastatin significantly reduces long-term cardiovascular events and deaths over 20 years in hypertensive patients, supporting early statin initiation for cardiovascular prevention.
The CONNECT trial demonstrates no significant difference in neoatherosclerosis rates 3 years post-STEMI between biodegradable and durable polymer everolimus-eluting stents, challenging assumptions about biodegradable polymers' superiority.
The PARAGLIDE-HF trial demonstrates that sacubitril/valsartan significantly reduces NT-proBNP in patients with LVEF >40% and worsening heart failure, regardless of left ventricular hypertrophy or left atrial enlargement, but patients with both abnormalities face higher hyperkalemia risk.
Empagliflozin alters peripheral microvascular responses in HFpEF patients, enhancing insulin-mediated vasodilation but reducing acetylcholine responsiveness, suggesting a targeted vascular mechanism distinct from general endothelial or smooth muscle effects.
Acute tetrahydrobiopterin (BH4) administration improves locomotor muscle microvascular function in heart failure patients, highlighting the nitric oxide pathway as a promising therapeutic target, while acute antioxidant therapy showed no benefit.
This study evaluates new contrast-derived indices of coronary microvascular function, highlighting their diagnostic potential and cost-effectiveness compared to traditional adenosine testing.
Dapagliflozin significantly improves metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis outcomes without increasing adverse events, according to a rigorous 48-week randomized trial.
A recent double-blind RCT shows iloprost did not reduce organ failure severity in septic shock patients with persistent hypoperfusion, highlighting challenges in improving outcomes despite theoretical benefits in microcirculation.
This article explores how microcirculation functions as a key regulator in normal pregnancy but is compromised in preeclampsia, revealing early hemodynamic mechanisms behind gestational hypertension.