Proton Beam vs IMRT for Olfactory Neuroblastoma: Multicenter Propensity-Matched Cohort Shows No Clear Superiority
Posted innews Oncology Otorhinolaryngology

Proton Beam vs IMRT for Olfactory Neuroblastoma: Multicenter Propensity-Matched Cohort Shows No Clear Superiority

A multicenter propensity-matched cohort comparing adjuvant proton beam radiotherapy (PBRT) with intensity-modulated radiotherapy (IMRT) for olfactory neuroblastoma found no definitive differences in local control, recurrence-free survival, overall survival, or clinically meaningful reductions in grade ≥2 radiation toxicities, but estimates were imprecise.
Radiotherapy for Growing Vestibular Schwannomas: Real‑World Tumor Control and What It Means for Practice
Posted innews Oncology Otorhinolaryngology

Radiotherapy for Growing Vestibular Schwannomas: Real‑World Tumor Control and What It Means for Practice

An international multicenter cohort of 1,883 patients with radiologically growing vestibular schwannomas treated first‑line with radiotherapy showed a 10‑year tumor control rate of 76.1% (primary definition). Control estimates varied widely by growth definition, underscoring the clinical importance of outcome metrics.
Adenotonsillectomy vs Watchful Waiting in Young Children with Mild–Moderate OSA: Long-term Findings from the KATE Randomized Trial
Posted innews Otorhinolaryngology Pediatrics

Adenotonsillectomy vs Watchful Waiting in Young Children with Mild–Moderate OSA: Long-term Findings from the KATE Randomized Trial

The KATE trial (n=60) found no between-group difference in polysomnographic OAHI change after 3 years, though adenotonsillectomy improved disease-specific quality of life. Nearly 42% of watchful-waiting children later underwent surgery, suggesting watchful waiting is reasonable for selected young children with mild OSA and small tonsils but requires close follow-up.
Temporary Inpatient Hemodialysis Access for Uninsured Patients Is Associated with Shorter Hospital Stays in a County Safety-Net System
Posted inNephrology news Public Health

Temporary Inpatient Hemodialysis Access for Uninsured Patients Is Associated with Shorter Hospital Stays in a County Safety-Net System

A Los Angeles County quality-improvement study found that regulatory approval allowing an inpatient hemodialysis unit to provide transitional outpatient dialysis to uninsured patients initiating hemodialysis was associated with a substantial, sustained reduction in hospital length of stay.
Antibody–Drug Conjugates and Heart Risk in HER2-Positive Advanced Breast Cancer: What Clinicians Need to Know
Posted inCardiology news Oncology

Antibody–Drug Conjugates and Heart Risk in HER2-Positive Advanced Breast Cancer: What Clinicians Need to Know

A 2025 meta-analysis of 9,538 patients found trastuzumab emtansine (T‑DM1) carries the lowest incidence of LVEF decline (0.94%), while trastuzumab deruxtecan (T‑DXd) and trastuzumab-based combinations show similar, modest rates (≈4–5%). Trial selection and monitoring practices limit generalizability; baseline cardiac assessment and individualized surveillance remain essential.
Therapist-Guided e‑Health Cuts Fear of Cancer Recurrence in Colorectal Survivors: A Randomized Trial Shows Clinically Meaningful Benefits
Posted inAI news Oncology

Therapist-Guided e‑Health Cuts Fear of Cancer Recurrence in Colorectal Survivors: A Randomized Trial Shows Clinically Meaningful Benefits

A Danish RCT of TG‑iConquerFear, a 10‑week therapist‑guided online program for colorectal cancer survivors with clinical fear of cancer recurrence (FCR), reduced FCR scores substantially compared with augmented self‑help at 3 months; the between‑group effect was clinically meaningful (Cohen d 0.62).