Posted innews
新诊断的儿童免疫性血小板减少症中使用艾曲波帕：早期治疗策略的突破
这项随机试验表明，艾曲波帕显著改善了新诊断为ITP的儿童的持续血小板反应，提供了一种潜在的早期干预选择。
Posted inCardiology news Pediatrics
Innovations in Atrial Septal Defect Closure: Comparing Bioresorbable and Metallic Occluders
This article reviews a landmark randomized trial demonstrating that bioresorbable occluders are noninferior to metallic ones in ASD closure, with implications for improved patient outcomes and device management.
Posted inCardiology news Oncology
Predicting Heart Failure Risk in Women Treated for Breast Cancer: A New Clinical Tool
A novel risk prediction model for 10-year heart failure or cardiomyopathy offers tailored cardiac management strategies for women undergoing breast cancer therapy.
Posted inDiabetes & Endocrinology news Ophthalmology
Impact of Multifactorial Interventions on Retinopathy in Type 2 Diabetes: Insights from the J-DOIT3 Trial
This analysis highlights how intensive multifactorial management and glycemic control influence diabetic retinopathy onset, emphasizing the risks associated with hypoglycemia despite good glycemic control.
Enhancing Postoperative Sexual Readiness in Urogynecologic Surgery: Insights from a Randomized Trial
A recent trial evaluates the effectiveness of counseling interventions on patient preparedness and sexual outcomes after pelvic surgeries.
Posted inEmergency Medicine news Plastic Surgery
Comprehensive Management of Animal Bites: Integrating Plastic Surgery and Predictive Algorithm Approaches
This article reviews injury profiles from animal bites, emphasizing plastic surgery roles, treatment strategies, and a predictive model for complications, based on a large clinical dataset from Balıkesir University.
Posted inAnesthesiology news Pediatrics Plastic Surgery
Customized Protective Palatal Obturator Enhances Safe Intubation in Neonatal Cleft Lip Surgery: Evidence from a Randomized Controlled Trial
A customized protective palatal obturator significantly reduces oral tissue injury during intubation in newborns undergoing cleft lip surgery, improving safety without prolonging intubation.
Posted innews Psychiatry Public Health
Unlocking the Complexity of Co-Occurring Chronic Pain and Psychological Distress in Young Adults: Insights from Machine Learning and Explainable AI
This study applies machine learning and explainable AI to identify factors associated with chronic pain, psychological distress, and their co-occurrence in Norwegian young adults, highlighting the importance of integrated approaches for early intervention.
Posted innews
Nâng cao chức năng nhai sau khi cắt bỏ xương hàm dưới do ung thư miệng: Các yếu tố quan trọng và ý nghĩa lâm sàng
Bài đánh giá này nêu bật các yếu tố đa phương của chức năng nhai ở bệnh nhân được phục hồi sau khi cắt bỏ xương hàm dưới, nhấn mạnh vai trò quan trọng của các hỗ trợ cắn phía sau.
Long-Term Outcomes of Oral Implant Rehabilitation in Patients with Disabilities Under General Anesthesia: A 14-Year Cohort Study
This study evaluates the safety, effectiveness, and longevity of implant-supported prostheses in disabled patients treated under general anesthesia over 14 years.
Posted inAI Cardiology news Rehabilitation Medicine
Harnessing Wearable Technology to Boost Cardiac Rehabilitation Adherence in CHD Patients: Insights from a Randomized Trial
This study evaluates how smartwatch-assisted home-based cardiac rehab improves exercise adherence and health outcomes in coronary heart disease patients.
Revolutionizing Cardiac Rehab: The Impact of Wearable Technology and Online Coaching
This review discusses a landmark study demonstrating how wearable devices and online coaching improve exercise capacity in coronary artery disease patients, highlighting advancements in remote cardiac rehabilitation.
Posted inNeurology news Rehabilitation Medicine
Electroacupuncture in Ischemic Stroke: Integrating Preclinical Evidence into Clinical Potential
This review synthesizes preclinical evidence on electroacupuncture's mechanisms in ischemic stroke, highlighting its therapeutic potential and factors influencing efficacy.
Long-Term Seizure Outcomes and Epilepsy Risk in Anti-LGI1 Encephalitis: Insights from a Multicenter Cohort Study
This study assesses seizure remission and epilepsy risk in 236 anti-LGI1 encephalitis patients, highlighting immunotherapy's role in seizure control and identifying biomarkers linked to persistent cognitive impairment and long-term outcomes.
Posted inNephrology news Rheumatology
Avacopan in Older Adults with ANCA-Associated Vasculitis: Efficacy and Safety Confirmed in ADVOCATE Post Hoc Analysis
This post hoc analysis of the ADVOCATE trial demonstrates that avacopan is effective and safe for treating ANCA-associated vasculitis in patients aged 65 and older, achieving sustained remission with reduced glucocorticoid exposure and toxicity compared to prednisone taper.
Posted inNephrology news Rheumatology
Avacopan Combined with Cyclophosphamide in ANCA-Associated Vasculitis: A Safer and Effective Alternative to Prednisone Taper
Avacopan, a complement C5a receptor inhibitor, shows comparable remission rates to prednisone taper in ANCA-associated vasculitis patients receiving cyclophosphamide, with benefits of lower relapse, improved kidney function, and reduced glucocorticoid toxicity.
Posted inNephrology news Rheumatology
Real-World Effectiveness of Rituximab and Cyclophosphamide in Severe ANCA-Associated Vasculitis: Insights from J-CANVAS
A comprehensive review of a Japanese cohort study assessing rituximab and cyclophosphamide efficacy in severe microscopic polyangiitis and GPA, highlighting clinical implications.
Long-Term Success of Satralizumab in Managing NMOSD: Insights from the SAkuraMoon Study
This article reviews the long-term safety and efficacy of satralizumab in neuromyelitis optica spectrum disorder based on the SAkuraMoon extension trial.
Enhancing Fertility Preservation and Ovarian Function in Young Women with Breast Cancer: Insights from International Prospective Studies
This article reviews a joint analysis of the Joven & Fuerte and PREFER studies, highlighting disparities in fertility preservation strategies among Mexican and Italian young women with breast cancer, and discusses implications for clinical practice.
Posted inHIV/AIDS Infectious Diseases news
Accelerated Epigenetic Aging in HIV: Insights from a Systematic Review
Systematic review evidence supports accelerated epigenetic aging in people living with HIV compared to uninfected individuals, highlighting the need for further research considering antiretroviral therapy and confounding factors.