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SLA-DR knockout

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SLA-DR–Deleted Donor Pigs Show Durable Kidney Xenograft Function and a Favorable Safety Profile in Rhesus Monkeys
Posted inGeneral Surgery Nephrology news

SLA-DR–Deleted Donor Pigs Show Durable Kidney Xenograft Function and a Favorable Safety Profile in Rhesus Monkeys

Posted by By MedXY 06/06/2026
CRISPR-engineered GGTA1/B4GALNT2/SLA-DR knockout pigs remained healthy, screened negative for 55 zoonotic pathogens, and supported long-term renal xenograft function in rhesus monkeys when preformed anti-SLA antibodies were absent.
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