Synergistic Effects of Combined Aerobic and Resistance Exercise with Diet on Insulin Secretion and Neurotrophic Factors in Older Adults with Obesity
Posted inClinical Updates Diabetes & Endocrinology Family Medicine & Nutrition news Specialties

Synergistic Effects of Combined Aerobic and Resistance Exercise with Diet on Insulin Secretion and Neurotrophic Factors in Older Adults with Obesity

Combining aerobic and resistance exercise with diet-induced weight loss in older adults with obesity significantly improves insulin secretion, metabolic health, and physical function, likely mediated by ciliary neurotrophic factor receptor preservation and increased IGF-1 levels.
Evaluating the Role of Estrogen Replacement Therapy Combined with Resistance Exercise in Older Women with Knee Osteoarthritis: Insights from a Randomised Clinical Trial
Posted inClinical Updates news Orthopedics Specialties

Evaluating the Role of Estrogen Replacement Therapy Combined with Resistance Exercise in Older Women with Knee Osteoarthritis: Insights from a Randomised Clinical Trial

This trial assessed the additive effects of low-dose transdermal estrogen replacement therapy combined with resistance exercise in women aged 65+ with knee osteoarthritis, finding no overall significant benefit but suggesting potential improvements in early-stage disease and mental health.