proteomics – Medxy AI

Beyond HDL-C: How Macronutrient Shifts Reshape HDL Subspecies to Reduce Coronary Risk

By MedXY 02/04/2026

The OmniHeart trial reveals that replacing dietary carbohydrates with unsaturated fats or protein favorably modifies 15 minor protein-based HDL subspecies, shifting the proteomic profile toward lower coronary heart disease risk, independent of total HDL-C levels.

Cardiology news

Proteomic Signatures in Atrial Fibrillation: Deciphering the Risk of Heart Failure Hospitalization and Ejection Fraction Phenotypes

By MedXY 01/22/2026

This study identifies key plasma biomarkers—including NT-proBNP, FGF-23, and GDF-15—that predict heart failure hospitalization in patients with atrial fibrillation. Findings also reveal distinct pathophysiological pathways for HFrEF and HFpEF, highlighting the roles of inflammation and adipose metabolism.

Cardiology Critical Care news

Plasma Proteomics Unveils VEGFR1 as a High-Precision Prognostic Biomarker in Cardiogenic Shock

By MedXY 01/18/2026

A large-scale proteomic analysis identifies VEGFR1 as a significant, independent predictor of 180-day mortality in patients with cardiogenic shock, offering incremental prognostic value beyond traditional markers like serum lactate and SAPS II scores.

Neurology news

Oligodendrocyte Myelin Glycoprotein: A Novel Plasma Determinant of Neurodegenerative Resiliency

By MedXY 01/07/2026

A comprehensive multi-cohort proteomic study identifies Oligodendrocyte Myelin Glycoprotein (OMG) as a causal biomarker for neurodegenerative resiliency, linking its peripheral abundance to axonal integrity and reduced risk of dementia and multiple sclerosis.

Medical News Neurology Pathology & Lab Medicine

Blood Test Breakthrough: Detecting ALS Over a Decade Before Symptoms Emerge

By MedXY 09/04/2025

New research identifies a protein signature in blood that detects ALS years before symptoms, challenging previous perceptions and offering hope for early diagnosis and intervention.

Cardiology news Specialties

Decoding Heart Failure Risk: Integrated Systolic and Diastolic Function Trajectories and Proteomic Insights

By MedXY 09/02/2025

Bayesian modelling of combined systolic and diastolic function trajectories in older adults reveals distinct patterns predicting heart failure subtypes and identifies potential proteomic targets for therapy.

Cardiology news Specialties

Decoding Cardiac Trajectories: Linking Systolic-Diastolic Function Patterns to Heart Failure Risk and Proteomics

By MedXY 09/02/2025

This study integrates longitudinal systolic and diastolic cardiac function measures using Bayesian modeling to identify trajectories associated with distinct heart failure subtypes and proteomic signatures, enhancing risk prediction and therapeutic target discovery.

Family Medicine & Nutrition news Specialties

The Cliff of Aging: Why Your Body Suddenly Feels Old at 30, 45, and 60

By MedXY 08/19/2025

New studies reveal that human aging is non-linear, with key biological shifts at 30, 45–55, and 60 years driving accelerated decline in endocrine function and tissue health.

Internal Medicine news

Decoding the Timetable of Organ Aging: Insights from Proteomic Studies

By MedXY 07/28/2025

A groundbreaking study reveals the aging patterns of human organs and identifies key proteins involved, paving the way for new anti-aging strategies.