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pathogenic variants

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Broad Genetic Testing Reveals Hidden Breast Cancer Risk in Women Without Family History
Posted innews Oncology

Broad Genetic Testing Reveals Hidden Breast Cancer Risk in Women Without Family History

Posted by MedXY By MedXY 12/16/2025
The WISDOM trial found that 3.1% of women without breast cancer carried pathogenic variants in key susceptibility genes, many outside existing testing guidelines.
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Quantifying Breast Cancer Risk: The Impact of Pathogenic Variants and Family History in US Women
Posted innews Oncology

Quantifying Breast Cancer Risk: The Impact of Pathogenic Variants and Family History in US Women

Posted by MedXY By MedXY 10/10/2025
This study evaluates cumulative breast cancer risks among US women based on pathogenic variant status and family history, revealing significant risk stratification that informs personalized screening and prevention.
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  • Pregnancy Complications Signal Long-Term Maternal Risk of Subarachnoid Hemorrhage in a 50-Year Swedish Cohort
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