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p16

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Radiotherapy Interruptions in Head and Neck Cancer Raise Risk of Locoregional Failure and Death — Impact Depends on p16 Status and Stage
Posted innews Oncology Otorhinolaryngology

Radiotherapy Interruptions in Head and Neck Cancer Raise Risk of Locoregional Failure and Death — Impact Depends on p16 Status and Stage

Posted by By MedXY 12/08/2025
Secondary analysis of three RTOG/NRG trials shows radiotherapy interruptions are associated with higher locoregional failure and worse overall survival in head and neck cancer, with larger absolute harms in p16‑negative and high‑stage disease.
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HPV-Positive Oropharyngeal Cancer Retains a Strong Survival Advantage After Surgery in Patients Aged ≥70
Posted innews Oncology Otorhinolaryngology

HPV-Positive Oropharyngeal Cancer Retains a Strong Survival Advantage After Surgery in Patients Aged ≥70

Posted by By MedXY 11/21/2025
In a multi-center cohort of 345 surgically treated patients aged 70 or older with tonsil or base‑of‑tongue SCC, p16 positivity was associated with substantially better 5‑year overall and disease‑free survival compared with p16‑negative tumors.
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  • 12,13-diHOME Levels as a Marker of Brown Adipose Tissue Activation and Outcome in Targeted Temperature Management Post-Cardiac Arrest
  • Transseptal TMVR Using the SAPIEN M3 System: 1-Year Outcomes in Patients with Mitral Annular Calcification from the ENCIRCLE MAC Registry
  • High-Impact Physical Activity and Joint Replacement Risk in Hip and Knee Osteoarthritis: A Large-Scale Longitudinal Mediation Study
  • Integrated Respiratory and Functional Training Enhances Weaning and Recovery After Emergency Abdominal Surgery: Insights from a Randomized Controlled Trial
  • Optimizing Peri-Implant Tissue Dimensions: Timing and Materials in Crestal Soft-Tissue Augmentation
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