older adults – Medxy AI

Preventing Falls in Care Homes: What the 2025 Cochrane Review Now Recommends

By MedXY 10/31/2025

An evidence-based synthesis of the 2025 Cochrane review on fall-prevention in care facilities: which interventions work, for whom, and how to implement them in practice.

Clinical Updates news Public Health

Effectiveness and Safety of RSV Vaccination in US Adults Aged 60 Years or Older: A Comprehensive Evidence Synthesis

By MedXY 10/31/2025

RSV vaccines demonstrate substantial effectiveness and acceptable safety profiles in adults aged ≥60, with diminished effectiveness in immunocompromised subgroups and a low, statistically significant increased risk of Guillain-Barré syndrome for certain formulations.

news Psychiatry Public Health

Gamified mHealth Strategies Boost Treatment Adherence and Outcomes in Late-Life Depression

By MedXY 10/27/2025

Implementing gamification in mobile health psychotherapy markedly improves adherence and reduces depressive symptoms among older adults, offering a promising avenue to address mental health care needs in aging populations.

Critical Care Emergency Medicine news Public Health Specialties

Empowering Older Adults in Acute Care: Insights on Shared Decision Making for Treatment Escalation Planning

By MedXY 10/20/2025

This qualitative UK study explores older patients' perspectives on shared decision making for treatment escalation during acute hospital deterioration, highlighting the need for patient autonomy, education, and adaptable clinical approaches.

HIV/AIDS Infectious Diseases Public Health Specialties

HIV Among Older Adults in Sub-Saharan Africa: Epidemiology, Risks, and Treatment Insights from the AWI-Gen Longitudinal Study

By MedXY 10/20/2025

This multicentre longitudinal cohort study reveals significant HIV prevalence and incidence among adults aged 40 and older in sub-Saharan Africa, highlighting age, gender, education, and rural residency as critical factors influencing HIV risk and treatment outcomes.

Internal Medicine news Public Health

Optimizing Healthy Ageing: The Impact of Physical Activity and Sedentary Behavior on Intrinsic Capacity in Older Adults

By MedXY 10/20/2025

This prospective Spanish cohort study reveals that moderate-to-vigorous physical activity enhances intrinsic capacity in older adults, while sedentary behavior impairs it, underscoring the role of active lifestyles in promoting healthy ageing.

news Psychiatry Public Health

Global Trends and Method-Specific Suicide Mortality Among Older Adults: Insights and Projections to 2050

By MedXY 10/20/2025

A comprehensive study spanning 47 countries reveals changing suicide mortality rates among adults aged 65+, highlighting method-specific risks and projecting future trends amid global population ageing.

Neurology news Public Health

Iyengar Yoga and Fall Risk in Older Adults: Unexpected Outcomes from a Rigorous RCT

By MedXY 10/20/2025

A large randomized controlled trial found that an Iyengar yoga-based exercise program increased fall rates among older adults compared to seated relaxation yoga, despite improvements in physical activity and balance confidence, highlighting the need for modified fall prevention yoga programs.

Neurology news Public Health

Optimizing Lifestyle Interventions to Prevent Cognitive Decline in Older Adults: Insights from a Comprehensive Network Meta-Analysis

By MedXY 10/20/2025

A large-scale network meta-analysis highlights that combined physical exercise and cognitive training most effectively improve cognition in older adults without impairment, emphasizing tailored lifestyle strategies for dementia prevention.

Infectious Diseases news Respiratory

Three-Season Protection Against RSV in Older Adults: Insights from the AReSVi-006 Phase 3 Trial of the AS01E-Adjuvanted RSVPreF3 OA Vaccine

By MedXY 10/04/2025

The AS01E-adjuvanted RSVPreF3 OA vaccine demonstrates robust efficacy against RSV-related lower respiratory tract disease over three seasons in adults aged 60+, with a favorable safety profile and promising immunogenicity findings.

Diabetes & Endocrinology Family Medicine & Nutrition news Specialties

Preserving Bone Quality in Older Adults with Obesity Through Lifestyle Intervention: Insights from the LIMB-Q Trial

By MedXY 09/29/2025

The LIMB-Q trial demonstrates that intensive lifestyle interventions combining weight management and exercise preserve bone quality in older adults with obesity, despite significant weight loss, highlighting a promising approach for mitigating osteoporosis risk during aging.

Family Medicine & Nutrition Nursing & care Specialties

Integrating Fall Prevention in Primary Care Significantly Reduces Falls Among Rural Older Adults in China: Insights from the FAMILY Cluster RCT

By MedXY 09/28/2025

A 12-month cluster randomized trial in rural China demonstrated that a fall prevention program integrated into primary health care significantly decreased fall risk among older adults, highlighting a scalable strategy for resource-limited settings with aging populations.

Cardiology Public Health Specialties

High-Dose vs Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults: Insights from the DANFLU-2 Randomized Clinical Trial and Related Evidence

By MedXY 09/27/2025

This review synthesizes evidence on high-dose versus standard-dose influenza vaccines for cardiovascular outcomes in older adults, focusing on the large DANFLU-2 trial and complementary studies, highlighting modest cardiovascular benefits and implications for clinical practice.

Clinical Updates news

Personalized Low-Dose Aspirin Use for Cancer Prevention in Older Adults

By MedXY 09/25/2025

A secondary analysis of the ASPREE trial reveals low-dose aspirin’s heterogeneous effects on cancer prevention in older adults, highlighting clonal hematopoiesis of indeterminate potential (CHIP) as a key predictor for benefit.

Clinical Updates news Nursing & care Orthopedics Specialties

Efficacy and Safety of Acupuncture for Chronic Low Back Pain in Older Adults: Results from a Multisite Randomized Clinical Trial

By MedXY 09/20/2025

A multisite randomized trial demonstrates that acupuncture, both standard and enhanced, significantly improves chronic low back pain-related disability in older adults compared to usual medical care, with sustained benefits and a favorable safety profile.

Clinical Updates Diabetes & Endocrinology Family Medicine & Nutrition news Specialties

Optimizing Metabolic and Physical Health in Obese Older Adults: Impact of Exercise Modalities on Insulin Secretion, CNTF, and IGF-1 During Weight Loss

By MedXY 09/17/2025

Combining aerobic and resistance exercise with diet-induced weight loss in obese older adults significantly improves insulin secretion, preserves CNTFRα levels, and increases IGF-1, enhancing metabolic and physical function.

Clinical Updates Diabetes & Endocrinology Family Medicine & Nutrition news Specialties

Synergistic Effects of Combined Aerobic and Resistance Exercise with Diet on Insulin Secretion and Neurotrophic Factors in Older Adults with Obesity

By MedXY 09/17/2025

Combining aerobic and resistance exercise with diet-induced weight loss in older adults with obesity significantly improves insulin secretion, metabolic health, and physical function, likely mediated by ciliary neurotrophic factor receptor preservation and increased IGF-1 levels.

Clinical Updates Family Medicine & Nutrition news Specialties

High-Protein Diet and Strength Training in Older Adults: No Adverse Impact on Oxidative Stress Markers

By MedXY 09/16/2025

A 17-week randomized controlled trial demonstrates that a high-protein diet combined with strength training does not negatively affect oxidative stress markers in older adults, supporting their safe use to combat sarcopenia.

Clinical Updates Neurology news

Inflammatory Exposure Amplifies Depressive Symptoms in Older Adults with Insomnia: Insights from a Randomized Clinical Trial

By MedXY 09/11/2025

A randomized clinical trial reveals older adults with insomnia have heightened depressive responses to inflammatory challenge, underscoring the need for targeted depression monitoring and prevention strategies in this vulnerable population.

Cardiology Clinical Updates news Nursing & care Specialties

Multidomain Rehabilitation Reduces Cardiovascular Events in Older Adults Post-Myocardial Infarction: Insights from the PIpELINe Trial

By MedXY 09/10/2025

A multidomain rehabilitation program combining cardiovascular risk control, dietary counseling, and exercise significantly lowers the risk of cardiovascular death or unplanned hospitalization within one year in older myocardial infarction survivors with impaired physical performance.