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Hydrocortisone in Preterm Infants and School-Age Functional Outcomes: Comprehensive Review of Evidence from Randomized Clinical Trials
Posted inClinical Updates news

Hydrocortisone in Preterm Infants and School-Age Functional Outcomes: Comprehensive Review of Evidence from Randomized Clinical Trials

Posted by By MedXY 12/08/2025
Neonatal hydrocortisone treatment in preterm infants at high risk for bronchopulmonary dysplasia does not improve school-age functional outcomes, highlighting the persistent burden of developmental impairment despite intervention.
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Acute Kidney Injury in Extremely Preterm Infants Predicts Higher Risk of Death or Neurodevelopmental Impairment at Two Years
Posted inNephrology news Pediatrics

Acute Kidney Injury in Extremely Preterm Infants Predicts Higher Risk of Death or Neurodevelopmental Impairment at Two Years

Posted by By MedXY 11/19/2025
Secondary analysis of the PENUT trial found that acute kidney injury (AKI) in infants born at 24–27 weeks’ gestation is independently associated with death or moderate to severe neurodevelopmental impairment at 22–26 months' corrected age.
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Decoding the Genetic Complexity of Impulsivity and Its Neurodevelopmental Impact
Posted inNeurology news Psychiatry

Decoding the Genetic Complexity of Impulsivity and Its Neurodevelopmental Impact

Posted by By MedXY 10/29/2025
This study reveals the heterogeneous genetic architecture of impulsivity, uncovering diverse biological pathways linking it to neurodevelopment and psychopathology across the lifespan.
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Silent Long-Term Harm: How Prenatal Lead Exposure Shapes Adult Mental Health
Posted inPediatrics Psychiatry Public Health

Silent Long-Term Harm: How Prenatal Lead Exposure Shapes Adult Mental Health

Posted by By MedXY 10/24/2025
This article explores the link between prenatal and early postnatal lead exposure and adult anxiety and depression, emphasizing critical exposure windows and long-term mental health implications.
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Long-Term Educational Trajectories After Preterm Birth: Unraveling the Roles of Biological and Sociodemographic Factors
Posted innews Pediatrics Specialties

Long-Term Educational Trajectories After Preterm Birth: Unraveling the Roles of Biological and Sociodemographic Factors

Posted by By MedXY 10/01/2025
This study reveals that although individuals born preterm face higher risks of lower educational attainment, sociodemographic factors have a greater impact on long-term educational outcomes than prematurity itself.
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Early-Life Gut Microbiome Maturity: A Key Regulator of Blood-Brain Barrier Integrity and Cognitive Development
Posted inClinical Updates Neurology Specialties

Early-Life Gut Microbiome Maturity: A Key Regulator of Blood-Brain Barrier Integrity and Cognitive Development

Posted by By MedXY 09/29/2025
This study demonstrates that the maturity of the early-life gut microbiome influences blood-brain barrier integrity and cognitive functions, highlighting a novel therapeutic target for neurodevelopmental disorders.
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Intranasal Mesenchymal Stromal Cells for Perinatal Arterial Stroke: Promising Safety and Improved Neurodevelopment at Two Years
Posted inClinical Updates Neurology OB/GYN & Women's Health

Intranasal Mesenchymal Stromal Cells for Perinatal Arterial Stroke: Promising Safety and Improved Neurodevelopment at Two Years

Posted by By MedXY 09/22/2025
The PASSIoN study shows that intranasally administered allogeneic mesenchymal stromal cells in neonates with perinatal arterial ischemic stroke are safe up to two years and suggest better motor outcomes compared to untreated cohorts.
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Innovations in Prenatal Care: In Utero Embolization for Vein of Galen Malformation
Posted inClinical Updates Neurology news OB/GYN & Women's Health Specialties

Innovations in Prenatal Care: In Utero Embolization for Vein of Galen Malformation

Posted by By MedXY 09/10/2025
In utero embolization for fetal Vein of Galen malformation shows early promise in reducing mortality and neurodevelopmental delays, despite increased risk of preterm delivery.
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  • Higher Mortality When Children on Mechanical Ventilation Are Cared for Outside ICUs: National Japanese Cohort Signals Need for Pediatric ICU Centralization
  • Targeting Tissue Perfusion and Lower MAP in Septic Shock Did Not Improve 30‑Day Perfusion-Free Survival: Results from the TARTARE-2S Randomized Trial
  • White Matter Microstructure and Cognitive Decline in Aging and Alzheimer Disease: A Comprehensive Review of Recent Advances
  • Phenylephrine Versus Norepinephrine in Acute Abdomen Surgery: Similar Clinical Outcomes but Different Early Renin Responses — Implications for Perioperative Hemodynamic Care
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