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HTLV-1

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A viral clonality evenness score accurately identifies HTLV‑1 carriers at high risk of adult T‑cell leukaemia
Posted inHematology-Oncology Infectious Diseases news

A viral clonality evenness score accurately identifies HTLV‑1 carriers at high risk of adult T‑cell leukaemia

Posted by MedXY By MedXY 11/27/2025
A clonality evenness score (VCE) derived from HTLV‑1 integration sequencing discriminates asymptomatic carriers who later develop adult T‑cell leukaemia from those who do not, outperforming proviral load alone in individual-level prediction in a Japanese longitudinal cohort.
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