Helicobacter pylori

Precision Genomics Outperforms Empirical Approaches in Managing Drug-Resistant Helicobacter pylori

By MedXY 12/29/2025

A global genomic study of Helicobacter pylori reveals that mutations in 23S rRNA and gyrA predict antibiotic resistance with 100% sensitivity, signaling the end of empirical therapy in favor of genotype-based personalized treatment.

Gastroenterology Infectious Diseases news

Optimized Bismuth Quadruple Therapy Surpasses Standard Triple Therapy for First-Line H. pylori Eradication

By MedXY 12/19/2025

A double-blind RCT in Chile demonstrates that a 14-day optimized bismuth quadruple therapy achieves a 95% eradication rate for Helicobacter pylori, significantly outperforming standard triple therapy without increasing the burden of adverse events.

Clinical Updates Gastroenterology news

Rifasutenizol-Based Triple Therapy Versus Bismuth Plus Clarithromycin Triple Therapy for First-Line Helicobacter pylori Eradication: Analysis of the EVEREST-HP Phase 3 Trial in China

By MedXY 11/24/2025

EVEREST-HP demonstrates that rifasutenizol-based triple therapy offers non-inferior H. pylori eradication with improved tolerability compared to bismuth plus clarithromycin triple therapy in treatment-naive Chinese patients.

Gastroenterology news Public Health

Taipei Global Consensus II (2025): A Practical Guide to Helicobacter pylori Screening and Eradication for Gastric Cancer Prevention

By MedXY 11/07/2025

An evidence-based synthesis of the 2025 Taipei Global Consensus II: 28 statements guiding H. pylori screening, eradication, surveillance and stewardship to reduce gastric cancer at individual and population levels.

Gastroenterology news Specialties

Enhancing Helicobacter pylori Eradication: The Role of Probiotics Pretreatment

By MedXY 09/02/2025

Probiotic pretreatment improves Helicobacter pylori eradication rates and reduces side effects, offering a promising adjunctive strategy to overcome treatment challenges and antibiotic resistance.

Cardiology Clinical Updates Gastroenterology Specialties

Routine Helicobacter pylori Screening Post-Myocardial Infarction: Insights from the HELP-MI SWEDEHEART Trial

By MedXY 09/02/2025

Routine H. pylori screening after acute myocardial infarction does not significantly reduce upper gastrointestinal bleeding incidence; targeted screening in anemia or kidney failure subgroups may offer benefit.

Cardiology Clinical Updates Gastroenterology news Specialties

Routine Helicobacter pylori Screening Post-Myocardial Infarction: Insights from the HELP-MI SWEDEHEART Trial

By MedXY 09/02/2025

In a large Swedish cluster-randomized trial, routine Helicobacter pylori screening after acute myocardial infarction did not significantly reduce upper gastrointestinal bleeding, though high-risk subgroups may benefit.

Clinical Updates news Oncology Specialties

Eradication of Helicobacter pylori Significantly Reduces Gastric Cancer Incidence and Mortality, with Clearer Benefits in High-Risk Populations

By MedXY 08/05/2025

A comprehensive meta-analysis confirms that Helicobacter pylori eradication reduces gastric cancer risk and related deaths, especially benefiting high-risk groups, supporting widespread screening and treatment.

Medical News news Oncology Specialties

Is Your Practice Missing the Next Gastric Cancer Surge?

By MedXY 08/03/2025

A new study predicts 11.8 million gastric cancer cases linked to Helicobacter pylori infection among children born 2008-2017, urging stronger global prevention and vaccine development.