Posted inClinical Updates news Psychiatry
Integrating Rare and Common Variants: The Synergistic Role of rCNVs and Polygenic Scores in Psychiatric Risk Stratification
This review synthesizes evidence on how recurrent copy number variants (rCNVs) and polygenic scores (PGSs) jointly influence psychiatric risk, highlighting their complementary roles in clinical risk assessment and the emergence of precision subtyping in neurodevelopmental disorders.