Posted inClinical Updates Dermatology Rheumatology
Targeting Nicotinamide N-Methyltransferase: A Novel Approach to Mitigate Fibroblast Activation and Skin Fibrosis in Systemic Sclerosis
This article explores the pivotal role of Nicotinamide N-methyltransferase (NNMT) in fibroblast activation and extracellular matrix deposition driving skin fibrosis in systemic sclerosis, highlighting therapeutic potential of NNMT inhibition.