Long-Term Survival Outweighs Short-Term Quality of Life: Why Esophagectomy Remains the Gold Standard for Esophageal Cancer Responders

Long-Term Survival Outweighs Short-Term Quality of Life: Why Esophagectomy Remains the Gold Standard for Esophageal Cancer Responders

A decision analytical model reveals that while active surveillance offers short-term quality-of-life benefits, standard esophagectomy provides superior 5-year survival and quality-adjusted life-years (QALYs) for esophageal cancer patients achieving clinical complete response after neoadjuvant therapy.
Long-Term Survival vs. Short-Term Quality of Life: Deciding the Fate of Esophageal Cancer Responders

Long-Term Survival vs. Short-Term Quality of Life: Deciding the Fate of Esophageal Cancer Responders

A decision analytical model based on the SANO trial suggests that while active surveillance offers short-term quality-of-life benefits, standard esophagectomy remains superior for maximizing long-term survival and quality-adjusted life-years in patients achieving a clinical complete response after neoadjuvant chemoradiation.